SCHEMBL15948159

SCHEMBL15948159

O=C(Cl)c1cc(C(=O)Cl)cc(C(O)(C(F)(F)F)C(F)(F)F)c1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.39
MLYCD O95822 8/20 0.39
RORC P51449 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
PGR P06401 3/20 0.36
NR1H3 Q13133 3/20 0.36
NR1H2 P55055 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1333906 0.81 LCK (0.43) CES2MLYCDRORCSMN1; SMN2NR1H3
SCHEMBL13199238 0.81 MRGPRX4 (0.40) MLYCDRORCSMN1; SMN2
SCHEMBL31078115 0.79 MLYCD (0.54) MLYCDRORCSMN1; SMN2NR1H3NR1H2
Hydrochloric Acid SCHEMBL15948160 0.79 LCK (0.42) CES2MLYCDRORCSMN1; SMN2NR1H3
SCHEMBL14593293 0.77 CES2 (0.45) CES2MLYCDRORCSMN1; SMN2NR1H3
SCHEMBL322157 0.76 CES2 (0.67) CES2
SCHEMBL8586265 0.74 NR1H2 (0.48) MLYCDRORCSMN1; SMN2PGRNR1H3
SCHEMBL38576 0.74 ALDH1A1 (0.40) CES2
SCHEMBL271349 0.71 RXRA (0.42) SMN1; SMN2
Hydrochloric Acid SCHEMBL18918955 0.71 ALDH1A1 (0.39) CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 US disclosed
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 US disclosed
EP-2395040-A1 FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM Central Glass Company, Limited (JP) 2011-12-14 EP disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom MCCC2, AFF2, F13A1 CES2 2110/4885MLYCD 740/4885RORC 3831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.