Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 19/20 | 0.52 |
| ▸ | PKLR | P30613 | 15/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004164 | 0.90 | RORC (0.44) | PKMPKLRLMNANPC1RAB9A | |
| SCHEMBL16004010 | 0.89 | PKM (0.55) | PKMPKLRLMNANPC1RAB9A | |
| SCHEMBL16004163 | 0.87 | PKM (0.49) | PKMPKLRLMNANPC1RAB9A | |
| SCHEMBL16004227 | 0.87 | PKM (0.43) | PKMPKLRLMNANPC1RAB9A | |
| SCHEMBL16004107 | 0.83 | PKM (0.45) | PKMPKLRLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL16004338 | 0.82 | LMNA (0.39) | PKMPKLRLMNASMN1; SMN2 | |
| SCHEMBL16004020 | 0.82 | PKM (0.40) | PKMPKLRLMNARAB9AKDM4E | |
| SCHEMBL16004262 | 0.82 | L3MBTL1 (0.45) | LMNANPC1RAB9AKDM4EGAA | |
| SCHEMBL16004006 | 0.82 | GPR142 (0.45) | PKMPKLRLMNANPC1RAB9A | |
| SCHEMBL16004325 | 0.82 | RORC (0.44) | PKMPKLRLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014133414-A2 | HETEROCYCLIC TGR5 BILE ACID RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR THE PRODUCTION AND USE THEREOF | АЛЛА ХЕМ ЛЛС (US) | 2014-09-04 | — | — | WO | disclosed |