Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 3/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15462269 | 0.87 | TNKS (0.61) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL12549643 | 0.82 | TP53 (0.59) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL13574150 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL14960024 | 0.75 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL12549503 | 0.74 | TNKS (0.59) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL12571746 | 0.73 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL12549588 | 0.73 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL13574158 | 0.70 | HPGD (0.53) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL11949810 | 0.65 | MAPK10 (0.57) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL6716039 | 0.64 | METTL3 (0.55) | KDM4EALDH1A1HPGDKMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140255426-A1 | WNT PATHWAY INHIBITORS FOR TREATING VIRAL INFECTIONS | EMORY UNIVERSITY (US) | 2014-09-11 | — | — | US | disclosed |