Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | BAD | Q92934 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062621 | 0.76 | MAPT (0.41) | CES2CES1KMT2ANOS3NOS1 | |
| SCHEMBL8463456 | 0.76 | ALDH1A1 (0.41) | CES2CES1ACHEMAOBMEN1 | |
| SCHEMBL3956678 | 0.71 | HPGD (0.43) | CES2CES1ACHECA1CA2 | |
| SCHEMBL6174528 | 0.71 | ALDH1A1 (0.41) | MAOBKMT2A | |
| SCHEMBL5645014 | 0.69 | MEN1 (0.44) | MEN1POLBKMT2ACA1CA2 | |
| Acetone SCHEMBL27946364 | 0.67 | CES2 (0.58) | CES2CES1ACHEMEN1POLB | |
| Acetic Acid SCHEMBL27477631 | 0.65 | CES2 (0.55) | CES2CES1ACHEMEN1POLB | |
| SCHEMBL27709 | 0.64 | — | — | |
| SCHEMBL303555 | 0.64 | — | — | |
| SCHEMBL1696183 | 0.64 | CES2 (0.62) | CES2CES1MAOBKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110637023-B | Dibenzopyrrole methine boron chelate compound, near infrared light absorbing material, thin film, and organic electronic device | 日本化药株式会社 | 2022-07-08 | — | — | CN | disclosed |
| US-10749116-B1 | Dibenzopyrromethene boron chelate compound, near-infrared light-absorbing material, thin-film, and organic electronic device | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2020-08-18 | — | — | US | disclosed |
| US-20200243774-A1 | Dibenzopyrromethene Boron Chelate Compound, Near-Infrared Light-Absorbing Material, Thin-Film, and Organic Electronic Device | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2020-07-30 | — | — | US | disclosed |
| CN-110637023-A | Dibenzopyrrole methine boron chelate compound, near-infrared light absorbing material, thin film and organic electronic device | 日本化药株式会社 | 2019-12-31 | — | — | CN | disclosed |
| EP-2091951-B1 | PYRIDO[2,3-B]PYRAZINE AND [1,8]-NAPHTHYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON INC (US) | 2018-02-28 | — | — | EP | disclosed |
| CN-101437819-B | Pyridopyrazines and derivatives thereof as alk and c-MET inhibitors | CEPHALON INC | 2013-06-19 | — | — | CN | disclosed |
| US-8080561-B2 | Pyridopyrazines and derivatives thereof as ALK and c-Met inhibitors | CEPHALON, INC. (US) | 2011-12-20 | — | — | US | disclosed |
| US-20110160204-A1 | PYRIDOPYRAZINES AND DERIVATIVES THEREOF AS ALK AND c-MET INHIBITORS | CEPHALON, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| US-7919502-B2 | Pyridopyrazines and derivatives thereof as ALK and c-MET inhibitors | CEPHALON, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20100048576-A1 | PYRIDOPYRAZINES AND DERIVATIVES THEREOF AS ALK AND c-MET INHIBITORS | CEPHALON, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-7601716-B2 | Pyridopyrazines and derivatives thereof as ALK and c-Met inhibitors | CEPHALON, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| EP-2091951-A2 | PYRIDO[2,3-B]PYRAZINE AND[1,8]-NAPHTYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2009-08-26 | — | — | EP | disclosed |
| CN-101437819-A | Pyridopyrazines and derivatives thereof as ALK and c-MET inhibitors | CEPHALON INC (US) | 2009-05-20 | — | — | CN | disclosed |
| US-20080032972-A1 | Pyridopyrazines and derivatives thereof as alk and c-Met inhibitors | CEPHALON, INC. (US) | 2008-02-07 | — | — | US | disclosed |
| WO-2007130468-A2 | PYRIDO [2, 3-B] PYRAZINE AND [1, 8] -NAPHTHYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200243774-A1 | Dibenzopyrromethene Boron Chelate Compound, Near-Infrared Light-Absorbing Material, Thin-Film, and Organic Electronic Device | CX3CR1, CRY1, PAX3 | CES2 3569/4885CES1 4191/4885ACHE 2798/4885 |
| US-20110160204-A1 | PYRIDOPYRAZINES AND DERIVATIVES THEREOF AS ALK AND c-MET INHIBITORS | ALK, MET, RET | CES2 2095/4885CES1 1472/4885ACHE 3670/4885 |
| US-10749116-B1 | Dibenzopyrromethene boron chelate compound, near-infrared light-absorbing material, thin-film, and organic electronic device | CX3CR1, CRY1, PAX3 | CES2 3512/4885CES1 4178/4885ACHE 2770/4885 |
| US-20100048576-A1 | PYRIDOPYRAZINES AND DERIVATIVES THEREOF AS ALK AND c-MET INHIBITORS | ALK, MET, RET | CES2 2095/4885CES1 1472/4885ACHE 3670/4885 |
| US-20080032972-A1 | Pyridopyrazines and derivatives thereof as alk and c-Met inhibitors | ALK, MET, RET | CES2 2095/4885CES1 1472/4885ACHE 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.