Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16016735 | 0.91 | THRA (0.41) | THRATHRBPDK1HCAR3HSD17B3 | |
| SCHEMBL1611987 | 0.90 | THRA (0.46) | THRATHRBHCAR3HSD17B3ALDH1A1 | |
| SCHEMBL1611950 | 0.81 | THRA (0.48) | THRATHRBPDK1HCAR3HSD17B3 | |
| SCHEMBL16016753 | 0.81 | ESR1 (0.55) | PDK1ESR1ALDH1A1MAPT | |
| SCHEMBL21319 | 0.80 | CASP6 (0.57) | PDK1HCAR3 | |
| SCHEMBL11765445 | 0.78 | LMNA (0.57) | THRATHRBHCAR3HSD17B3ALDH1A1 | |
| SCHEMBL16016718 | 0.78 | THRA (0.41) | THRATHRBPDK1HCAR3HSD17B3 | |
| SCHEMBL16016763 | 0.77 | THRA (0.40) | THRATHRBPDK1HCAR3HSD17B3 | |
| SCHEMBL28029786 | 0.77 | HCAR3 (0.53) | THRATHRBHCAR3HSD17B3GAA | |
| SCHEMBL2949996 | 0.77 | VCAM1 (0.54) | PDK1HCAR3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920084-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2018-03-20 | — | — | US | disclosed |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | RNGTT, OSTC, OSGEP | THRA 3708/4885THRB 3613/4885PDK1 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.