SCHEMBL16093971

SCHEMBL16093971

COC(=O)C(C)SC(=S)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 3/20 0.46
LMNA P02545 1/20 0.46
GLA P06280 1/20 0.46
TSHR P16473 1/20 0.46
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
MEN1 O00255 1/20 0.43
PLA2G1B P04054 1/20 0.43
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
ESRRB O95718 1/20 0.41
GAA P10253 1/20 0.41
THRB P10828 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22204637 0.88 ELANE (0.40) KMT2AALDH1A1LMNAGLATSHR
SCHEMBL3749730 0.83 MEN1 (0.51) KMT2AALDH1A1LMNATSHRMEN1
SCHEMBL13533998 0.82 SMN1; SMN2 (0.41) ALDH1A1LMNATSHRPTGS1PTGS2
SCHEMBL13873963 0.81 GAA (0.40) KMT2AALDH1A1LMNAGLAMEN1
SCHEMBL22204638 0.81 ELANE (0.42) KMT2AALDH1A1LMNAGLAMEN1
SCHEMBL21242986 0.80 CES2 (0.42) KMT2AALDH1A1LMNATSHRMEN1
SCHEMBL2893483 0.80 KMT2A (0.51) KMT2AALDH1A1LMNAGLATSHR
SCHEMBL237873 0.80 KMT2A (0.51) KMT2AALDH1A1LMNAGLATSHR
SCHEMBL24596015 0.79 RXRA (0.38) KMT2AALDH1A1LMNAGLAPTGS1
SCHEMBL29151606 0.79 ALDH1A1 (0.39) KMT2AALDH1A1LMNAGLATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
US-11886045-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-01-30 US claimed
US-11834383-B2 Energetic feedstock for additive manufacturing LYNNTECH, INC. (US) 2023-12-05 US claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
US-20230339149-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-10-26 US claimed
EP-4240578-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-09-13 EP claimed
US-11708446-B2 Polymers and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-07-25 US claimed
WO-2022097048-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-12 WO claimed
US-20220137433-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-05 US claimed
US-20210276931-A1 Energetic Feedstock for Additive Manufacturing LYNNTECH, INC. 2021-09-09 US claimed
US-20210221937-A1 POLYMERS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-07-22 US claimed
US-11041026-B2 Reactions enabled by thermoresponsive and photoresponsive gels MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-06-22 US claimed
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US disclosed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US disclosed
US-20260007755-A1 SELF-ASSEMBLED DIBLOCK COPOLYMERS COMPOSED OF PEGMEMA AND DRUG BEARING POLYMERIC SEGMENTS RS ARASTIRMA EGITIM DANISMANLIK ILAC SANAYI TICARET ANONIM SIRKETI (TR) 2026-01-08 US disclosed
US-20160145426-A1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & COMPANY 2016-05-26 US disclosed
WO-2014152453-A2 CONTINUOUS FLOW SYNTHESIS OF DITHIOESTER COMPOUNDS SIGMA-ALDRICH CO. LLC (US) 2014-09-25 WO disclosed
WO-2014152453-A2 CONTINUOUS FLOW SYNTHESIS OF DITHIOESTER COMPOUNDS SIGMA-ALDRICH CO. LLC (US) 2014-09-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA KMT2A 3102/4885ALDH1A1 1404/4885LMNA 50/4885
US-20260007755-A1 SELF-ASSEMBLED DIBLOCK COPOLYMERS COMPOSED OF PEGMEMA AND DRUG BEARING POLYMERIC SEGMENTS CLTB, F13B, FGB KMT2A 3337/4885ALDH1A1 4682/4885LMNA 1896/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA KMT2A 3092/4885ALDH1A1 905/4885LMNA 1320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.