Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13396768 | 0.89 | FNTA (0.37) | PTGS2PTGS1 | |
| SCHEMBL20104860 | 0.80 | ALDH1A1 (0.36) | PTGS2PTGS1 | |
| SCHEMBL16124632 | 0.79 | KMT2A (0.36) | PTGS2KMT2A | |
| SCHEMBL13396705 | 0.78 | FNTA (0.44) | — | |
| SCHEMBL20113580 | 0.77 | FAAH (0.39) | PTGS2PTGS1 | |
| SCHEMBL13396691 | 0.77 | SLC6A5 (0.46) | — | |
| SCHEMBL5183160 | 0.76 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL13396744 | 0.76 | NOD1 (0.44) | — | |
| SCHEMBL13863668 | 0.75 | TSHR (0.41) | PTGS2PTGS1 | |
| SCHEMBL20104867 | 0.75 | HPGD (0.39) | PTGS2PTGS1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | PTGS2 15/4885PTGS1 8/4885KMT2A 4323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.