Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16669141 | 0.83 | FFAR4 (0.39) | GPR84SLC22A6FFAR4FFAR1LMNA | |
| SCHEMBL4939304 | 0.81 | FOLH1 (0.35) | SLC22A6FFAR4FFAR1LMNA | |
| SCHEMBL4943234 | 0.81 | FOLH1 (0.35) | SLC22A6FFAR4FFAR1LMNA | |
| SCHEMBL4180699 | 0.80 | PGD (0.33) | SLC22A6PGD | |
| SCHEMBL4455207 | 0.80 | PGD (0.33) | SLC22A6PGD | |
| SCHEMBL4180706 | 0.80 | PGD (0.33) | SLC22A6PGD | |
| SCHEMBL13619245 | 0.80 | CA2 (0.31) | — | |
| SCHEMBL4317383 | 0.77 | GABRP (0.41) | MAPT | |
| SCHEMBL4317387 | 0.77 | GABRP (0.41) | MAPT | |
| SCHEMBL20582003 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9534008-B2 | Small molecule compounds that control plant- and insect-pathogenic nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-01-03 | — | — | US | disclosed |
| US-9487551-B2 | Small molecule compounds that control mammal-pathogenic nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-11-08 | — | — | US | disclosed |
| US-9445596-B2 | Small molecule compounds for the control of nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| US-20140364386-A1 | Small Molecule Compounds That Control Plant- and Insect-Pathogenic Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140303102-A1 | Small Molecule Compounds that Control Mammal-Pathogenic Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-10-09 | — | — | US | disclosed |
| US-20140303360-A1 | Small Molecule Compounds for the Control of Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303360-A1 | Small Molecule Compounds for the Control of Nematodes | MAVS, EMG1, PINK1 | GPR84 1268/4885ACACB 731/4885ACACA 1470/4885 |
| US-20140364386-A1 | Small Molecule Compounds That Control Plant- and Insect-Pathogenic Nematodes | HNMT, EMG1, API5 | GPR84 4338/4885ACACB 855/4885ACACA 1105/4885 |
| US-20140303102-A1 | Small Molecule Compounds that Control Mammal-Pathogenic Nematodes | EMG1, HNMT, MSN | GPR84 3577/4885ACACB 298/4885ACACA 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.