Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960122 | 1.00 | MEN1 (0.53) | MEN1KMT2AMAPTCYP1A2GAA | |
| SCHEMBL2866190 | 0.94 | MAPT (0.58) | MEN1KMT2AMAPTCYP1A2GAA | |
| SCHEMBL30544458 | 0.94 | MAPT (0.58) | MEN1KMT2AMAPTCYP1A2GAA | |
| SCHEMBL226987 | 0.89 | MEN1 (0.51) | MEN1KMT2AMAPTCYP1A2GAA | |
| SCHEMBL3953142 | 0.89 | MEN1 (0.51) | MEN1KMT2AMAPTCYP1A2GAA | |
| SCHEMBL1615065 | 0.87 | KMT2A (0.53) | MEN1KMT2AMAPTCYP1A2GAA | |
| SCHEMBL18038402 | 0.86 | KMT2A (0.53) | MEN1KMT2AMAPTCYP1A2GAA | |
| SCHEMBL1615061 | 0.86 | KMT2A (0.53) | MEN1KMT2AMAPTCYP1A2GAA | |
| SCHEMBL5940611 | 0.84 | MEN1 (0.53) | MEN1KMT2AMAPTCYP1A2GAA | |
| SCHEMBL30893167 | 0.83 | MEN1 (0.47) | MEN1KMT2AMAPTCYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126167-A1 | OPTICAL DATA RECORDING MEDIA AND METHODS FOR RECORDING AND READING DATA THEREON | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2009-10-15 | — | — | WO | claimed |
| WO-2006049732-A1 | COLOR FORMING COMPOSITIONS AND ASSOCIATED METHODS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2006-05-11 | — | — | WO | claimed |
| US-20060093958-A1 | Color forming compositions and associated methods | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2006-05-04 | — | — | US | claimed |
| US-20060078832-A1 | Compositions for multi-color, light activated imaging | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2006-04-13 | — | — | US | claimed |
| US-8722167-B2 | Image recording media, methods of making image recording media, imaging layers, and methods of making imaging layers | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2014-05-13 | — | — | US | disclosed |
| US-8652607-B2 | Image recording media and imaging layers | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2014-02-18 | — | — | US | disclosed |
| EP-1940629-B1 | IMAGE RECORDING MEDIA AND IMAGE LAYERS | HEWLETT PACKARD DEVELOPMENT CO (US) | 2013-09-25 | — | — | EP | disclosed |
| US-8283100-B2 | Color forming compositions and associated methods | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2012-10-09 | — | — | US | disclosed |
| US-7968166-B2 | Optical recording system | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-06-28 | — | — | US | disclosed |
| EP-1834325-B1 | COLOR FORMING COMPOSITIONS WITH IMPROVED MARKING SENSITIVITY AND IMAGE CONTRAST AND ASSOCIATED METHODS | HEWLETT PACKARD DEVELOPMENT CO (US) | 2011-06-08 | — | — | EP | disclosed |
| US-20110111336-A1 | Compositions and Methods for High Efficiency Absorption of Radiation, and Films Formed Thereof | YewSavin, Inc. (US) | 2011-05-12 | — | — | US | disclosed |
| US-20110108773-A1 | Compositions for Depositions and Processing of Films for Electronic Applications | YewSavin, Inc. (US) | 2011-05-12 | — | — | US | disclosed |
| US-20060188828-A1 | Media for laser imaging | HEWLETT-PACKARD DEVELOPMENT COPMANY, L.P. | 2006-08-24 | — | — | US | disclosed |
| WO-2006073801-A2 | COLOR FORMING COMPOSITIONS WITH IMPROVED MARKING SENSITIVITY AND IMAGE CONTRAST AND ASSOCIATED METHODS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2006-07-13 | — | — | WO | disclosed |
| US-20060147833-A1 | Color forming compositions with improved marking sensitivity and image contrast and associated methods | KASPERCHIK VLADEK P | 2006-07-06 | — | — | US | disclosed |
| WO-2006049732-A1 | COLOR FORMING COMPOSITIONS AND ASSOCIATED METHODS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2006-05-11 | — | — | WO | disclosed |
| US-20060093958-A1 | Color forming compositions and associated methods | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2006-05-04 | — | — | US | disclosed |
| WO-2006038996-A1 | COLOR FORMING COMPOSITIONS AND ASSOCIATED METHODS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2006-04-13 | — | — | WO | disclosed |
| US-20060078832-A1 | Compositions for multi-color, light activated imaging | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2006-04-13 | — | — | US | disclosed |
| US-20060068315-A1 | Color forming compositions and associated methods | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2006-03-30 | — | — | US | disclosed |