Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 12/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544458 | 1.00 | MAPT (0.58) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1615063 | 0.94 | MEN1 (0.53) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL29960122 | 0.94 | MEN1 (0.53) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL30893167 | 0.89 | MEN1 (0.47) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL342266 | 0.84 | MAPT (0.75) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1615065 | 0.83 | KMT2A (0.53) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3953142 | 0.82 | MEN1 (0.51) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL226987 | 0.82 | MEN1 (0.51) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL29756485 | 0.82 | MEN1 (0.42) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL18038402 | 0.82 | KMT2A (0.53) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020178-B1 | Dental bleaching system and method | ADDENT INC (US) | 2003-10-01 | — | — | EP | claimed |
| EP-1020178-A1 | Dental bleaching system and method | AdDent Inc. (US) | 2000-07-19 | — | — | EP | claimed |
| US-6036493-A | Dental bleaching system and method | AD DENT INC. (US) | 2000-03-14 | — | — | US | claimed |
| US-11384381-B2 | Reaction accelerating agent | KIKKOMAN CORPORATION (JP) | 2022-07-12 | — | — | US | disclosed |
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-03-17 | — | — | US | disclosed |
| US-20190316174-A1 | REACTION ACCELERATING AGENT | KIKKOMAN CORPORATION (JP) | 2019-10-17 | — | — | US | disclosed |
| US-20180303977-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-10-25 | — | — | US | disclosed |
| US-7713472-B2 | Antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-05-11 | — | — | US | disclosed |
| US-7651661-B2 | Medical devices with broad spectrum antimicrobial activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-01-26 | — | — | US | disclosed |
| US-20080183152-A1 | MEDICAL DEVICES WITH BROAD SPECTRUM ANTIMICROBIAL ACTIVITY | RAAD ISSAM | 2008-07-31 | — | — | US | disclosed |
| US-20070154621-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2007-07-05 | — | — | US | disclosed |
| US-20050197634-A1 | Methods for coating and impregnating medical devices with antiseptic compositions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2005-09-08 | — | — | US | disclosed |
| EP-1020178-B1 | Dental bleaching system and method | ADDENT INC (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-1020178-A1 | Dental bleaching system and method | AdDent Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| US-6036493-A | Dental bleaching system and method | AD DENT INC. (US) | 2000-03-14 | — | — | US | disclosed |
| US-5807604-A | SOLVENT MIXTURE COMPRISING TARTRAZINE YELLOW AND AQUEOUS ETHYLENE GLYCOL | PRESERVED BOTANICALS, INC. (US) | 1998-09-15 | — | — | US | disclosed |
| US-5693361-A | SOAKING NATURAL PLANT MATERIALS IN AQUEOUS SOLUTION CONTAINING ETHYLENE GLYCOL AND DISSOLVED CARBON DIOXIDE, FOR DECORATIONS | PRESERVED BOTANICALS, INC. (US) | 1997-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | CUTA, CD63, CDC37 | MAPT 3347/4885NPC1 1401/4885RAB9A 3719/4885 |
| US-20180303977-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | CUTA, CD63, CDC37 | MAPT 3347/4885NPC1 1401/4885RAB9A 3719/4885 |
| US-11384381-B2 | Reaction accelerating agent | MPO, AOX1, MAOA | MAPT 4544/4885NPC1 4786/4885RAB9A 3015/4885 |
| US-20190316174-A1 | REACTION ACCELERATING AGENT | MPO, AOX1, MAOA | MAPT 4544/4885NPC1 4786/4885RAB9A 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.