Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616053 | 0.92 | ALDH1A1 (0.31) | — | |
| SCHEMBL1617843 | 0.91 | MEN1 (0.32) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL583416 | 0.90 | ALDH1A1 (0.31) | — | |
| SCHEMBL1616316 | 0.86 | — | — | |
| SCHEMBL1617774 | 0.86 | — | — | |
| SCHEMBL1617835 | 0.86 | — | — | |
| SCHEMBL1617886 | 0.84 | — | — | |
| SCHEMBL1617626 | 0.84 | — | — | |
| SCHEMBL1616026 | 0.84 | TSHR (0.33) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL584337 | 0.84 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | SYMRISE AG (DE) | 2025-05-22 | — | — | US | claimed |
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | SYMRISE AG (DE) | 2025-02-27 | — | — | US | claimed |
| WO-2025026525-A1 | HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS | SYMRISE AG (DE) | 2025-02-06 | — | — | WO | claimed |
| EP-4469439-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-12-04 | — | — | EP | claimed |
| EP-4452941-A1 | ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-10-30 | — | — | EP | claimed |
| US-20240058259-A1 | COMPOSITIONS COMPRISING ESSENTIAL OILS | FIRMENICH SA (CH) | 2024-02-22 | — | — | US | claimed |
| CN-117479843-A | Composition for enhancing cooling effect | 弗门尼舍公司 | 2024-01-30 | — | — | CN | claimed |
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | SYMRISE AG (DE) | 2024-01-04 | — | — | US | claimed |
| EP-3494104-B1 | WARMING SENSATION COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2023-11-15 | — | — | EP | claimed |
| EP-4247791-A2 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2023-09-27 | — | — | EP | claimed |
| WO-2014198366-A1 | GLOVE WITH A COOLING EFFECT | CARL FREUDENBERG KG (DE) | 2014-12-18 | — | — | WO | claimed |
| US-20140348756-A1 | WATER-FREE FORMULATIONS HAVING A COOLING EFFECT | HENKEL AG & CO. KGAA (DE) | 2014-11-27 | — | — | US | claimed |
| EP-2785309-A1 | COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT | Henkel AG & Co. KGaA (DE) | 2014-10-08 | — | — | EP | claimed |
| US-20140271518-A1 | COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT | HENKEL AG & CO. KGAA (DE) | 2014-09-18 | — | — | US | claimed |
| EP-2758029-A1 | WATER-FREE FORMULATIONS HAVING A COOLING EFFECT | Henkel AG&Co. KGAA (DE) | 2014-07-30 | — | — | EP | claimed |
| EP-2725900-A1 | ANTIMICROBIAL COMPOSITION | Takasago International Corporation (JP) | 2014-05-07 | — | — | EP | claimed |
| WO-2013079349-A1 | COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT | HENKEL AG & CO. KGAA (DE) | 2013-06-06 | — | — | WO | claimed |
| WO-2013041611-A1 | WATER-FREE FORMULATIONS HAVING A COOLING EFFECT | HENKEL AG & CO. KGAA (DE) | 2013-03-28 | — | — | WO | claimed |
| WO-2013002421-A1 | ANTIMICROBIAL COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-01-03 | — | — | WO | claimed |
| US-20130005807-A1 | ANTIMICROBIAL COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-01-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140348756-A1 | WATER-FREE FORMULATIONS HAVING A COOLING EFFECT | CUTA, RDX, POLR1C | MEN1 3796/4885KMT2A 2689/4885THRB 1285/4885 |
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | TAS2R5, TAS2R7, TAS2R8 | MEN1 714/4885KMT2A 2748/4885THRB 1845/4885 |
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | TTPA, TREH, TAS2R45 | MEN1 1761/4885KMT2A 4030/4885THRB 3272/4885 |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | TTR, TAS2R5, TAS2R50 | MEN1 766/4885KMT2A 3992/4885THRB 3565/4885 |
| US-20140271518-A1 | COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT | ALOX5, CUTA, OR51E2 | MEN1 1017/4885KMT2A 907/4885THRB 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.