Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697587 | 0.84 | MAOB (0.49) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL21951946 | 0.80 | PNMT (0.50) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL376144 | 0.79 | PNMT (0.45) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL28066660 | 0.79 | PNMT (0.49) | PNMTRAB9ANPC1HTR2BDRD2 | |
| SCHEMBL895389 | 0.78 | CTSS (0.46) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL10736267 | 0.77 | CD69 (0.53) | PNMTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL20886911 | 0.76 | L3MBTL1 (0.50) | PNMTDRD2MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL5749931 | 0.76 | PNMT (0.54) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL8068048 | 0.76 | PNMT (0.46) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL5745826 | 0.76 | HTR1B (0.53) | PNMTRAB9ANPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210061893-A1 | Diagnostic Kit | PHOENIX PHARMACEUTICALS, INC. (US) | 2021-03-04 | — | — | US | disclosed |
| US-10836812-B2 | Phoenixin peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2020-11-17 | — | — | US | disclosed |
| EP-2714717-B1 | PHOENIXIN PEPTIDES | PHOENIX PHARMACEUTICALS INC (US) | 2017-07-05 | — | — | EP | disclosed |
| US-20170145083-A1 | Phoenixin Peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2017-05-25 | — | — | US | disclosed |
| US-9534045-B2 | Phoenixin peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2017-01-03 | — | — | US | disclosed |
| US-20150322141-A1 | Phoenixin Peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2015-11-12 | — | — | US | disclosed |
| US-9018350-B2 | Phoenixin peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-20140163202-A1 | Phoenixin Peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| WO-2012162679-A1 | PHOENIXIN PEPTIDES | PHOENIX PHARMACEUTICALS, INC. (US) | 2012-11-29 | — | — | WO | disclosed |
| US-7928186-B2 | Cell permeable bioactive peptide conjugates | PHOENIX PHARMACEUTICALS, INC. (US) | 2011-04-19 | — | — | US | disclosed |
| US-20060275321-A1 | Polypeptide antagonists of HIV-1 Tat protein | PHOENIX PHARMACEUTICALS, INC. | 2006-12-07 | — | — | US | disclosed |
| US-7094869-B2 | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH, INC. (US) | 2006-08-22 | — | — | US | disclosed |
| US-20060063807-A1 | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH, INC. (US) | 2006-03-23 | — | — | US | disclosed |
| US-20050203015-A1 | Angiogenesis regulation system | PHOENIX PHARMACEUTICALS, INC. | 2005-09-15 | — | — | US | disclosed |
| US-6835806-B2 | Stable water soluble polypeptides which are potent inhibitors of endothelial cell proliferation and of angiogenesis. | PHOENIX PHARMACEUTICALS, INC. | 2004-12-28 | — | — | US | disclosed |
| US-20020111461-A1 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | SOMERS TODD C (US) | 2002-08-15 | — | — | US | disclosed |
| US-20020058620-A1 | Cell growth regulation system | PHOENIX PHARMACEUTICALS, INC. (US) | 2002-05-16 | — | — | US | disclosed |
| EP-0792289-B1 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | GENENTECH INC (US) | 2000-07-12 | — | — | EP | disclosed |
| EP-0999220-A2 | Low molecular weight peptidomimetic growth hormone secretagogues | Genentech, Inc. (US) | 2000-05-10 | — | — | EP | disclosed |
| US-6034216-A | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH INC. (US) | 2000-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111461-A1 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | GHSR, GHRHR, IGFBP1 | PNMT 3422/4885RAB9A 3541/4885NPC1 4238/4885 |
| US-20060063807-A1 | Low molecular weight peptidomimetic growth hormone secretagogues | GHSR, GHRHR, IGFBP1 | PNMT 3364/4885RAB9A 3557/4885NPC1 4304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.