Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984566 | 0.94 | NQO1 (0.58) | NQO1TSHRTDP1LTA4HALDH1A1 | |
| SCHEMBL11812608 | 0.84 | NQO1 (0.52) | NQO1TSHRTDP1LTA4HRELA | |
| SCHEMBL1007565 | 0.82 | LTA4H (0.53) | TSHRLTA4HSMN1; SMN2CA12CA1 | |
| SCHEMBL163688 | 0.82 | LTA4H (0.52) | LTA4HSMN1; SMN2CA12CA1CA2 | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.82 | NQO1 (1.00) | NQO1TSHRTDP1LTA4HALDH1A1 | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.82 | NQO1 (1.00) | NQO1TSHRTDP1LTA4HALDH1A1 | |
| SCHEMBL12344398 | 0.81 | L3MBTL1 (0.46) | NQO1KDM4E | |
| SCHEMBL10990102 | 0.81 | KMT2A (0.61) | ALDH1A1PARP10PRSS1MAPTNPC1 | |
| SCHEMBL31160399 | 0.80 | NQO1 (0.74) | NQO1TSHRTDP1LTA4H | |
| SCHEMBL20969950 | 0.80 | PRSS1 (0.41) | NQO1ALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036798-A | Gold (I) complex containing benzene ring ligand, preparation method thereof and application thereof in preparation of antitumor drugs | 西南医科大学附属医院 | 2026-05-15 | — | — | CN | claimed |
| US-20250122132-A1 | NITRIFICATION INHIBITORS | LINCOLN UNIVERSITY (NZ) | 2025-04-17 | — | — | US | claimed |
| EP-3990417-B1 | IMPROVEMENTS IN AND RELATING TO NITRIFICATION INHIBITORS | LINCOLN UNIV (NZ) | 2024-03-27 | — | — | EP | claimed |
| US-20230202941-A1 | NITRIFICATION INHIBITORS | LINCOLN UNIVERSITY (NZ) | 2023-06-29 | — | — | US | claimed |
| CN-115867525-A | Improvements in and relating to nitrification inhibitors | 林肯大学 | 2023-03-28 | — | — | CN | claimed |
| US-11578013-B2 | Nitrification inhibitors | LINCOLN UNIVERSITY (NZ) | 2023-02-14 | — | — | US | claimed |
| CN-114874088-A | Acetylenic acid and preparation method thereof | 中国科学院上海高等研究院 | 2022-08-09 | — | — | CN | claimed |
| US-20220153655-A1 | NITRIFICATION INHIBITORS | LINCOLN UNIVERSITY (NZ) | 2022-05-19 | — | — | US | claimed |
| EP-3990417-A1 | IMPROVEMENTS IN AND RELATING TO NITRIFICATION INHIBITORS | Lincoln University (NZ) | 2022-05-04 | — | — | EP | claimed |
| WO-2021242122-A1 | IMPROVEMENTS IN AND RELATING TO NITRIFICATION INHIBITORS | LINCOLN UNIVERSITY (NZ) | 2021-12-02 | — | — | WO | claimed |
| CN-109400518-B | Polysubstituted 6-arylbenzo [ a ] carbazole derivative and synthetic method thereof | 湘潭大学 | 2021-09-24 | — | — | CN | claimed |
| CN-111909356-A | Medical polyurethane material and preparation method thereof | 温州大学新材料与产业技术研究院 | 2020-11-10 | — | — | CN | claimed |
| EP-3362450-B1 | N1- AND N7-SUBSTITUTED SIBIRILINE DERIVATIVES AND THEIR USE AS INHIBITORS OF CELLULAR NECROPTOSIS | INST NAT SANTE RECH MED (FR) | 2020-07-01 | — | — | EP | claimed |
| US-20180312502-A1 | N1-And N7-Substituted Sibiriline Derivatives And Their Use As Inhibitor Of Cellular Necroptosis | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-11-01 | — | — | US | claimed |
| EP-3362450-A1 | N1- AND N7-SUBSTITUTED SIBIRILINE DERIVATIVES AND THEIR USE AS INHIBITOR OF CELLULAR NECROPTOSIS | Institut National de la Sante et de la Recherche Medicale (INSERM) (FR) | 2018-08-22 | — | — | EP | claimed |
| WO-2017064216-A1 | N1- AND N7-SUBSTITUTED SIBIRILINE DERIVATIVES AND THEIR USE AS INHIBITOR OF CELLULAR NECROPTOSIS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-04-20 | — | — | WO | claimed |
| CN-122036798-A | Gold (I) complex containing benzene ring ligand, preparation method thereof and application thereof in preparation of antitumor drugs | 西南医科大学附属医院 | 2026-05-15 | — | — | CN | disclosed |
| US-20250122132-A1 | NITRIFICATION INHIBITORS | LINCOLN UNIVERSITY (NZ) | 2025-04-17 | — | — | US | disclosed |
| EP-0306505-A1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES. | MERCK PATENT GMBH (DE) | 1989-03-15 | — | — | EP | disclosed |
| WO-1988007523-A1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202941-A1 | NITRIFICATION INHIBITORS | NOS1, NOS2, NOS3 | NQO1 74/4885TSHR 3480/4885TDP1 936/4885 |
| US-11578013-B2 | Nitrification inhibitors | NOS1, NOS2, NOS3 | NQO1 74/4885TSHR 3480/4885TDP1 936/4885 |
| US-20250122132-A1 | NITRIFICATION INHIBITORS | NOS1, NOS2, NOS3 | NQO1 74/4885TSHR 3480/4885TDP1 936/4885 |
| US-20220153655-A1 | NITRIFICATION INHIBITORS | NOS1, NOS2, NOS3 | NQO1 74/4885TSHR 3480/4885TDP1 936/4885 |
| US-20180312502-A1 | N1-And N7-Substituted Sibiriline Derivatives And Their Use As Inhibitor Of Cellular Necroptosis | CASP7, RIPK3, PARK7 | NQO1 1497/4885TSHR 4144/4885TDP1 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.