SCHEMBL16388489

SCHEMBL16388489

CC(C)(C)C(=O)CNC(=O)CBr

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.34
TRPA1 O75762 1/20 0.32
VDR P11473 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23643337 0.79 RECQL (0.35) RECQLVDRGAA
SCHEMBL20802464 0.79 MEN1 (0.46) RECQLVDRGAA
SCHEMBL19323273 0.77 HPGD (0.42) RECQLGAA
SCHEMBL3467454 0.77 ALDH1A1 (0.44) RECQLVDRGAA
SCHEMBL12617509 0.77 TERT (0.38) RECQLVDRGAA
SCHEMBL21850085 0.76 CA1 (0.34) RECQLVDR
SCHEMBL8056854 0.76 RECQL (0.33) RECQLVDR
SCHEMBL22345261 0.74 RECQL (0.61) RECQLGAA
SCHEMBL21099972 0.74 RECQL (0.55) RECQLGAA
SCHEMBL4742448 0.74 RECQL (0.41) RECQLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741018-A2 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2026-05-13 EP disclosed
EP-4739680-A1 SOLID FORMS OF TRPV4 ANTAGONISTS Actio Biosciences, Inc. (US) 2026-05-13 EP disclosed
US-12583836-B2 Sulphonamide compounds Anaxis Pharma Pty Ltd (AU) 2026-03-24 US disclosed
EP-4168401-B1 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2026-01-07 EP disclosed
US-20250333403-A1 THERAPEUTIC COMPOUNDS AND METHODS ACTIO BIOSCIENCES INC (US) 2025-10-30 US disclosed
US-12391683-B2 Therapeutic compounds and methods ACTIO BIOSCIENCES, INC. (US) 2025-08-19 US disclosed
EP-4551572-A1 THERAPEUTIC COMPOUNDS AND METHODS Actio Biosciences, Inc. (US) 2025-05-14 EP disclosed
US-20250074891-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-03-06 US disclosed
WO-2025014818-A1 SOLID FORMS OF GSK2798745, A TRPV4 ANTAGONIST ACTIO BIOSCIENCES, INC. (US) 2025-01-16 WO disclosed
EP-4452966-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2024-10-30 EP disclosed
WO-2023115149-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 WO disclosed
EP-4168401-A1 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-04-26 EP disclosed
CN-115956070-A Sulfonamide compounds 阿纳克西斯制药股份有限公司 2023-04-11 CN disclosed
WO-2021253095-A1 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2021-12-23 WO disclosed
US-20200251667-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES UDC IRELAND LTD (IE) 2020-08-06 US disclosed
EP-3608329-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES UDC Ireland Limited (IE) 2020-02-12 EP disclosed
EP-3266789-B1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES UDC IRELAND LTD (IE) 2019-09-25 EP disclosed
EP-3016960-B1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES UDC IRELAND LTD (IE) 2017-04-26 EP disclosed
US-20160372687-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES BASF SE (DE) 2016-12-22 US disclosed
WO-2015000955-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES BASF SE (DE) 2015-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333403-A1 THERAPEUTIC COMPOUNDS AND METHODS TRPV4, TRPV3, TRPV2 RECQL 2226/4885TRPA1 8/4885VDR 274/4885
US-20250074891-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS MLKL, RIPK3, CASP9 RECQL 4370/4885TRPA1 2181/4885VDR 4274/4885
US-12583836-B2 Sulphonamide compounds MLKL, RIPK3, CASP1 RECQL 4220/4885TRPA1 2336/4885VDR 1898/4885
US-20200251667-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES DDT, OCIAD1, OCIAD2 RECQL 4390/4885TRPA1 75/4885VDR 118/4885
US-12391683-B2 Therapeutic compounds and methods TRPV4, TRPV3, TRPV2 RECQL 2226/4885TRPA1 8/4885VDR 274/4885
US-20160372687-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES DDT, OCIAD1, OCIAD2 RECQL 4390/4885TRPA1 75/4885VDR 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.