Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16449706 | 0.67 | MEN1 (0.31) | MEN1ALPLMAPK1KMT2A | |
| SCHEMBL9056340 | 0.67 | KDM4E (0.36) | BRD4MEN1ALPLMAPK1KMT2A | |
| SCHEMBL15328628 | 0.63 | BRD4 (0.56) | BRD4MEN1ALPLMAPK1KMT2A | |
| SCHEMBL5004730 | 0.60 | MAPK1 (0.54) | BRD4MEN1ALPLMAPK1KMT2A | |
| SCHEMBL6256987 | 0.60 | PGR (0.44) | BRD4 | |
| SCHEMBL6262202 | 0.58 | PGR (0.46) | MEN1KMT2A | |
| SCHEMBL17231977 | 0.58 | — | — | |
| SCHEMBL11332957 | 0.58 | BRD4 (0.43) | BRD4 | |
| SCHEMBL11625099 | 0.58 | ALDH1A1 (0.31) | — | |
| SCHEMBL18020453 | 0.57 | GSK3A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160369045-A1 | NOVEL FUSED NAPHTHALENE CYCLOHETERO RING COMPOUNDS, AND METHODS AND USES THEREOF | CORNING INC (US) | 2016-12-22 | — | — | US | disclosed |
| US-20150065722-A1 | FUSED THIOPHENE DITIN MONOMERS | CORNING INCORPORATED | 2015-03-05 | — | — | US | disclosed |
| US-20150045560-A1 | NOVEL FUSED NAPHTHALENE CYCLOHETERO RING COMPOUNDS, AND METHODS AND USES THEREOF | CORNING INCORPORATED | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065722-A1 | FUSED THIOPHENE DITIN MONOMERS | TTL, THEM6, ITK | BRD4 1730/4885MEN1 870/4885ALPL 3134/4885 |
| US-20150045560-A1 | NOVEL FUSED NAPHTHALENE CYCLOHETERO RING COMPOUNDS, AND METHODS AND USES THEREOF | FDPS, PPOX, DHPS | BRD4 1952/4885MEN1 2211/4885ALPL 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.