Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GPX4 | P36969 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PER2 | O15055 | 1/20 | 0.30 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.30 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246146 | 0.88 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1GPX4KDM4EHCRTR2 | |
| SCHEMBL1648139 | 0.86 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1GPX4KDM4EHCRTR2 | |
| SCHEMBL19711906 | 0.86 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1GPX4KDM4EHCRTR2 | |
| SCHEMBL31314973 | 0.86 | ESR1 (0.36) | ALDH1A1L3MBTL1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL2812724 | 0.86 | ESR1 (0.36) | ALDH1A1L3MBTL1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL30096475 | 0.82 | ESR1 (0.48) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9879557 | 0.82 | ESR1 (0.48) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| Water SCHEMBL31143099 | 0.81 | ESR1 (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL2907159 | 0.79 | KMT2A (0.35) | ALDH1A1L3MBTL1MAPTMEN1HPGD | |
| SCHEMBL30114899 | 0.79 | KMT2A (0.35) | ALDH1A1L3MBTL1MAPTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3258273-B1 | A KIT AND METHOD FOR DETECTING CREATININE | PEKING UNION MEDICAL COLLEGE HOSPITAL CAMS (CN) | 2020-05-06 | — | — | EP | disclosed |
| EP-3258273-A1 | A KIT AND METHOD FOR DETECTING CREATININE | Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CN) | 2017-12-20 | — | — | EP | disclosed |
| US-20110129816-A1 | DEVICE FOR DETECTION OF INFLUENZA VIRUS | NATIONAL UNIVERSITY CORPORATION UNIVERSITY OF TOYAMA (JP) | 2011-06-02 | — | — | US | disclosed |
| EP-2309264-A1 | DEVICE FOR DETECTION OF INFLUENZA VIRUS | National University Corporation University Of Toyama (JP) | 2011-04-13 | — | — | EP | disclosed |
| US-6936473-B2 | For separating collected blood into blood cell and blood plasma, right on the spot of collection; for preparing sample for quantification used for clinical diagnosis | LEISURE, INC. (JP) | 2005-08-30 | — | — | US | disclosed |
| US-20050130323-A1 | Inhibitor for adhesion of metal hydroxide-containing substance to waste liquor line of automatic analyzer | KYOWA MEDEX CO. LTD. (JP) | 2005-06-16 | — | — | US | disclosed |
| EP-1477811-A1 | INHIBITOR OF THE ADHESION OF METAL OXIDE-CONTAINING MATERIAL TO WASTE LIQUOR LINE OF AUTOMATIC ANALYZER | KYOWA MEDEX CO., LTD. (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-20040141888-A1 | For separating collected blood into blood cell and blood plasma, right on the spot of collection; efficiency, simplification | LEISURE, INC. (JP) | 2004-07-22 | — | — | US | disclosed |
| US-20020153316-A1 | For separating collected blood into blood cell and blood plasma, right on the spot of collection; for preparing sample for quantification used for clinical diagnosis | LEISURE, INC. (JP) | 2002-10-24 | — | — | US | disclosed |
| EP-1221614-A2 | Instrument and method for blood separation, and preparing method, quantifying method and preserving container for biological sample | Leisure, Inc. (JP) | 2002-07-10 | — | — | EP | disclosed |