Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | APEX1 | P27695 | 3/20 | 0.55 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.54 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.54 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.48 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14001583 | 1.00 | ENPP2 (0.60) | ENPP2CYP1A2APEX1SENP2SUMO2 | |
| SCHEMBL11226640 | 0.91 | ENPP2 (0.67) | ENPP2CYP1A2APEX1SENP2SUMO2 | |
| SCHEMBL11226638 | 0.91 | ENPP2 (0.67) | ENPP2CYP1A2APEX1SENP2SUMO2 | |
| SCHEMBL29533645 | 0.90 | APEX1 (0.70) | ENPP2CYP1A2APEX1SENP2SUMO2 | |
| SCHEMBL14133503 | 0.87 | APEX1 (0.50) | ENPP2CYP1A2APEX1SENP2SUMO2 | |
| SCHEMBL11339046 | 0.86 | ENPP2 (0.61) | ENPP2CYP1A2APEX1SENP2SUMO2 | |
| SCHEMBL11317617 | 0.85 | ENPP2 (0.60) | ENPP2CYP1A2APEX1SENP2SUMO2 | |
| SCHEMBL15113036 | 0.84 | ENPP2 (0.54) | ENPP2CYP1A2APEX1SENP2SUMO2 | |
| SCHEMBL7790539 | 0.83 | SENP2 (0.68) | ENPP2CYP1A2APEX1SENP2SUMO2 | |
| SCHEMBL7790541 | 0.83 | SENP2 (0.68) | ENPP2CYP1A2APEX1SENP2SUMO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9364403-B2 | Hair treatment methods | PERACHEM LIMITED (GB) | 2016-06-14 | — | — | US | disclosed |
| US-9320695-B2 | Hair treatment methods | PERACHEM LIMITED (GB) | 2016-04-26 | — | — | US | disclosed |
| US-20150068548-A1 | Hair Treatment Methods | HSNF LIMITED (GB) | 2015-03-12 | — | — | US | disclosed |
| US-20150047131-A1 | Hair Treatment Methods | HSNF LIMITED (GB) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150068548-A1 | Hair Treatment Methods | TST, OAT, SLC14A1 | ENPP2 4286/4885CYP1A2 1824/4885APEX1 1758/4885 |
| US-20150047131-A1 | Hair Treatment Methods | POLR1C, SHH, DNMT3A | ENPP2 4483/4885CYP1A2 1803/4885APEX1 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.