Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.70 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
| ▸ | DUSP5 | Q16690 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.44 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14001583 | 0.90 | ENPP2 (0.60) | APEX1ENPP2CYP1A2SUMO2SUMO1 | |
| SCHEMBL16490261 | 0.90 | ENPP2 (0.60) | APEX1ENPP2CYP1A2SUMO2SUMO1 | |
| SCHEMBL11317610 | 0.86 | APEX1 (0.65) | APEX1APPENPP2DUSP5CYP1A2 | |
| SCHEMBL14133503 | 0.85 | APEX1 (0.50) | APEX1APPENPP2CYP1A2SUMO2 | |
| SCHEMBL29623460 | 0.82 | APEX1 (1.00) | APEX1APPENPP2DUSP5CYP1A2 | |
| SCHEMBL11670477 | 0.82 | APEX1 (1.00) | APEX1APPENPP2DUSP5CYP1A2 | |
| SCHEMBL29625848 | 0.82 | APEX1 (0.64) | APEX1APPENPP2DUSP5CYP1A2 | |
| SCHEMBL11670218 | 0.82 | APEX1 (0.66) | APEX1APPENPP2DUSP5CYP1A2 | |
| SCHEMBL29637808 | 0.81 | APEX1 (0.60) | APEX1APPENPP2DUSP5CYP1A2 | |
| SCHEMBL11226640 | 0.81 | ENPP2 (0.67) | APEX1ENPP2CYP1A2SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547208-B1 | PROCESS FOR REMOVING THE COLOUR FROM PREVIOUSLY DYED KERATINOUS HAIR FIBRES | OREAL (FR) | 2026-05-27 | — | — | EP | disclosed |
| US-12636246-B2 | Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound | L'OREAL (FR) | 2026-05-26 | — | — | US | disclosed |
| CN-122094656-A | Method for dyeing hair keratin fibres, comprising the step of washing the hair keratin fibres with a particular composition and subsequently applying to the hair keratin fibres a particular dyeing composition | — | 2026-05-26 | — | — | CN | disclosed |
| WO-2026039882-A1 | METHODS FOR REDUCING COLOR FADING IN COLOR-TREATED HAIR | L'OREAL (FR) | 2026-02-26 | — | — | WO | disclosed |
| US-20260027027-A1 | FRAGRANCED COMPOSITION COMPRISING AT LEAST ONE SULFUR-COMPRISING ANTIOXIDANT COMPOUND, AT LEAST ONE ORGANIC UV SCREENING AGENT AND AT LEAST ONE FRAGRANCING SUBSTANCE | OREAL (FR) | 2026-01-29 | — | — | US | disclosed |
| US-12533303-B2 | Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition | L'OREAL (FR) | 2026-01-27 | — | — | US | disclosed |
| US-20260007583-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2026-01-08 | — | — | US | disclosed |
| US-20250381106-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| US-20250381107-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| US-20250375361-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-11 | — | — | US | disclosed |
| WO-2022129346-A1 | COMPOSITION FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES AND PROCESS EMPLOYING THIS COMPOSITION | L'OREAL (FR) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129157-A1 | COMPOSITION COMPRISING AT LEAST ONE SILICONE OF FORMULA (I), AT LEAST ONE SILICONE OF FORMULA (II) AND AT LEAST ONE COLORING AGENT | L'OREAL (FR) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129347-A1 | COMPOSITION FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES AND PROCESS USING THIS COMPOSITION | L'OREAL (FR) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129343-A1 | PROCESS FOR LIGHTENING KERATIN FIBRES | L'OREAL (FR) | 2022-06-23 | — | — | WO | disclosed |
| US-20220183944-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING A DIRECT DYE AND AN ALIPHATIC AMMONIUM SALT, AND COMPOSITION COMPRISING SAME | L'OREAL (FR) | 2022-06-16 | — | — | US | disclosed |
| CN-111094474-B | Near-infrared-curable ink composition, near-infrared-curable film, method for producing near-infrared-curable film, and method for photo-molding | 住友金属矿山株式会社 | 2022-06-07 | — | — | CN | disclosed |
| CN-114574036-A | Ink, method for manufacturing ink, and inkjet system | 株式会社理光 | 2022-06-03 | — | — | CN | disclosed |
| US-20220169877-A1 | INK, METHOD FOR PRODUCING INK, AND INKJET SYSTEM | RICOH COMPANY, LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
| EP-3986366-A1 | COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE, AT LEAST ONE NON-AMINO SILICONE AND WATER, THE ALKOXYSILANE/NON-AMINO SILICONE MASS RATIO RANGING FROM 95/5 TO 5/95 | L'OREAL (FR) | 2022-04-27 | — | — | EP | disclosed |
| CN-114340588-A | Composition comprising at least one alkoxysilane of formula (I), at least one alkoxysilane of formula (II), at least one non-amino silicone and optionally a pigment and/or direct dye | 莱雅公司 | 2022-04-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12533303-B2 | Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition | KRT18, CA12, CA7 | THRB 2468/4885APEX1 598/4885APP 2885/4885 |
| US-20260027027-A1 | FRAGRANCED COMPOSITION COMPRISING AT LEAST ONE SULFUR-COMPRISING ANTIOXIDANT COMPOUND, AT LEAST ONE ORGANIC UV SCREENING AGENT AND AT LEAST ONE FRAGRANCING SUBSTANCE | CBR3, CBR1, ERCC1 | THRB 3716/4885APEX1 462/4885APP 2792/4885 |
| US-20250381106-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, VIM, MAP1LC3A | THRB 4386/4885APEX1 460/4885APP 1498/4885 |
| US-20260007583-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, F12, VIM | THRB 3644/4885APEX1 243/4885APP 2606/4885 |
| US-12636246-B2 | Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound | KRT18, CYC1, CYBA | THRB 1477/4885APEX1 989/4885APP 3927/4885 |
| US-20250375361-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, VIM, MAP1LC3A | THRB 4388/4885APEX1 407/4885APP 1578/4885 |
| US-20220183944-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING A DIRECT DYE AND AN ALIPHATIC AMMONIUM SALT, AND COMPOSITION COMPRISING SAME | KRT18, MARK1, IK | THRB 4055/4885APEX1 1217/4885APP 1106/4885 |
| US-20250381107-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, VIM, MAP1LC3A | THRB 4273/4885APEX1 392/4885APP 1608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.