Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.36 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501083 | 0.72 | TGFBR1 (0.38) | IRAK4TGFBR1ACVR1B | |
| SCHEMBL16512869 | 0.71 | ESR2 (0.46) | MAPTKDM4E | |
| SCHEMBL11850083 | 0.66 | TGFBR1 (0.46) | IRAK4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL246878 | 0.65 | ADORA1 (0.48) | TGFBR1GRM5MAPTALOX5KDM4E | |
| SCHEMBL24095387 | 0.64 | TGFBR1 (0.38) | IRAK4TGFBR1GRM5MAPT | |
| SCHEMBL24142605 | 0.64 | HTR3E (0.44) | IRAK4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13968416 | 0.63 | MAPT (0.49) | MAPTALOX5KDM4E | |
| SCHEMBL15984783 | 0.62 | HTR3E (0.50) | IRAK4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL14620840 | 0.62 | LMNA (0.43) | MAPTKDM4E | |
| SCHEMBL21297851 | 0.62 | L3MBTL1 (0.42) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380818-A | Pyrazolo pyridine compound, and pharmaceutical composition, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-04-22 | — | — | CN | disclosed |