Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL30731322 | 1.00 | LTA4H (0.39) | LTA4HNR5A1TSHRNPC1RAB9A | |
| SCHEMBL17916653 | 0.99 | LTA4H (0.40) | LTA4HNR5A1TSHRNPC1RAB9A | |
| Bicarbonate SCHEMBL17911341 | 0.91 | TP53 (0.39) | TSHRTP53 | |
| Iodide SCHEMBL18824159 | 0.89 | FGFR1 (0.38) | NPC1RAB9ATP53GAAFGFR1 | |
| Bicarbonate SCHEMBL29765454 | 0.82 | TP53 (0.41) | TSHRTP53 | |
| Bicarbonate SCHEMBL29765538 | 0.82 | TP53 (0.41) | TSHRTP53 | |
| Bicarbonate SCHEMBL26607957 | 0.82 | TP53 (0.41) | TSHRTP53 | |
| Bicarbonate SCHEMBL26607969 | 0.82 | TP53 (0.41) | TSHRTP53 | |
| SCHEMBL23366511 | 0.81 | ADRB2 (0.33) | — | |
| SCHEMBL18844586 | 0.80 | APAF1 (0.38) | LTA4HCASRLMNAMAPTAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12623250-B2 | Carbene-functionalized composite materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2026-05-12 | — | — | US | disclosed |
| US-12409473-B2 | Carbene-functionalized composite materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2025-09-09 | — | — | US | disclosed |
| US-20240351063-A1 | Carbene-Functionalized Composite Materials | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2024-10-24 | — | — | US | disclosed |
| US-20240173741-A1 | Carbene-Functionalized Composite Materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2024-05-30 | — | — | US | disclosed |
| US-11840766-B2 | Etching metal using N-heterocyclic carbenes | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2023-12-12 | — | — | US | disclosed |
| US-11801528-B2 | Carbene-functionalized composite materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2023-10-31 | — | — | US | disclosed |
| US-20220258202-A1 | Carbene-Functionalized Composite Materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2022-08-18 | — | — | US | disclosed |
| US-11383266-B2 | Carbene-functionalized composite materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2022-07-12 | — | — | US | disclosed |
| US-11008291-B2 | Methods of forming carbene-functionalized composite materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2021-05-18 | — | — | US | disclosed |
| US-20200283911-A1 | ETCHING METAL USING N-HETEROCYCLIC CARBENES | GREENCENTRE CANADA (CA) | 2020-09-10 | — | — | US | disclosed |
| US-20190169132-A1 | Methods of Forming Carbene-Functionalized Composite Materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2019-06-06 | — | — | US | disclosed |
| WO-2017075704-A1 | METHODS OF FORMING CARBENE-FUNCTIONALIZED COMPOSITE MATERIALS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2017-05-11 | — | — | WO | disclosed |
| US-20160199875-A1 | Carbene-Functionalized Composite Materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2016-07-14 | — | — | US | disclosed |
| EP-3036102-A1 | CARBENE FUNCTIONALIZED COMPOSITE MATERIALS | Queen's University At Kingston (CA) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015024120-A1 | CARBENE FUNCTIONALIZED COMPOSITE MATERIALS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2015-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12623250-B2 | Carbene-functionalized composite materials | EPCAM, CAD, CTTN | LTA4H 4757/4885NR5A1 1360/4885TSHR 1119/4885 |
| US-11008291-B2 | Methods of forming carbene-functionalized composite materials | VCL, CHN2, CA3 | LTA4H 1152/4885NR5A1 1236/4885TSHR 1595/4885 |
| US-20190169132-A1 | Methods of Forming Carbene-Functionalized Composite Materials | VCL, CHN2, CA3 | LTA4H 1152/4885NR5A1 1236/4885TSHR 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.