Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | TCF4 | P15884 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10224709 | 1.00 | CLPP (0.38) | CLPPCYP3A4ALDH1A1KCNA5CCR5 | |
| SCHEMBL744695 | 1.00 | CLPP (0.38) | CLPPCYP3A4ALDH1A1KCNA5CCR5 | |
| SCHEMBL16523994 | 0.95 | CTSK (0.38) | CLPPCYP3A4ALDH1A1KCNA5CCR5 | |
| SCHEMBL744694 | 0.95 | CTSK (0.38) | CLPPCYP3A4ALDH1A1KCNA5CCR5 | |
| SCHEMBL10224716 | 0.95 | CTSK (0.38) | CLPPCYP3A4ALDH1A1KCNA5CCR5 | |
| SCHEMBL747599 | 0.94 | ALDH1A1 (0.38) | CLPPCYP3A4ALDH1A1KMT2A | |
| SCHEMBL747186 | 0.94 | METAP2 (0.40) | CLPPCYP3A4ALDH1A1KMT2A | |
| SCHEMBL746174 | 0.94 | METAP2 (0.40) | CLPPCYP3A4ALDH1A1KMT2A | |
| SCHEMBL16524015 | 0.93 | CCR5 (0.42) | CLPPCYP3A4CCR5TCF4CTNNB1 | |
| SCHEMBL750763 | 0.93 | CCR5 (0.42) | CLPPCYP3A4CCR5TCF4CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150057283-A1 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO | CHOONGWAE PHARMA CORPORATION (KR) | 2015-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057283-A1 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO | WNT1, APC, WNT3 | CLPP 4096/4885CYP3A4 4757/4885ALDH1A1 4305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.