Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15999650 | 0.89 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14932583 | 0.86 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14932582 | 0.84 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL20271297 | 0.82 | LMNA (0.43) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19962267 | 0.78 | FOS (0.40) | L3MBTL1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL17991473 | 0.77 | PLAU (0.33) | ALDH1A1KDM4EPLAU | |
| SCHEMBL18927067 | 0.77 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17315802 | 0.77 | S1PR1 (0.41) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16771895 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HPGDMEN1KMT2AGPR35 | |
| SCHEMBL30452081 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HPGDMEN1KMT2AGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868719-B2 | Compounds with pesticidal activity | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-16 | — | — | US | disclosed |
| US-9776967-B2 | Carboxamide derivatives as pesticidal compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| US-9776967-B2 | Carboxamide derivatives as pesticidal compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| US-20170217931-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | BAYER ANIMAL HEALTH GMBH (DE) | 2017-08-03 | — | — | US | disclosed |
| US-20170217931-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | BAYER ANIMAL HEALTH GMBH (DE) | 2017-08-03 | — | — | US | disclosed |
| EP-3039018-B1 | PYRIDYL CARBOXAMIDE DERIVATIVES WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2017-08-02 | — | — | EP | disclosed |
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-14 | — | — | US | disclosed |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-14 | — | — | US | disclosed |
| WO-2016012485-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | BAYER ANIMAL HEALTH GMBH (DE) | 2016-01-28 | — | — | WO | disclosed |
| WO-2015055535-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2015-04-23 | — | — | WO | disclosed |
| WO-2015028427-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2015-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217931-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | ACHE, COX5B, TUBB6 | L3MBTL1 2180/4885ALDH1A1 177/4885HPGD 239/4885 |
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ACHE, DDT, NIT2 | L3MBTL1 3148/4885ALDH1A1 819/4885HPGD 1358/4885 |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | ACHE, DDT, CAT | L3MBTL1 2968/4885ALDH1A1 929/4885HPGD 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.