Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564132 | 0.77 | KMT2A (0.44) | POLBRAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL16563942 | 0.77 | KDM4E (0.40) | RAB9AKMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL16563837 | 0.76 | ALDH1A1 (0.39) | RAB9AKMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL16563623 | 0.74 | ALOX15 (0.42) | POLBRAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL16564046 | 0.73 | P2RX7 (0.47) | POLBRAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL16563605 | 0.73 | MEN1 (0.45) | RAB9AKMT2ASMN1; SMN2NPC1TP53 | |
| SCHEMBL16563648 | 0.72 | MAPT (0.52) | POLBRAB9A | |
| SCHEMBL16563570 | 0.72 | HTT (0.40) | POLBRAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL16563847 | 0.72 | MEN1 (0.47) | POLBRAB9AKMT2ANPC1 | |
| SCHEMBL16563497 | 0.72 | PTGES (0.39) | POLBRAB9AKMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848615-A1 | New pyrazole derivatives as CRAC channel modulators | Almirall, S.A. (ES) | 2015-03-18 | — | — | EP | claimed |
| EP-2848615-A1 | New pyrazole derivatives as CRAC channel modulators | Almirall, S.A. (ES) | 2015-03-18 | — | — | EP | disclosed |