Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646422 | 1.00 | ALOX5AP (0.44) | ALOX5APFEN1ARKIF11ALDH1A1 | |
| SCHEMBL2167740 | 0.85 | KIF11 (0.57) | ALOX5APFEN1ARKIF11ALDH1A1 | |
| SCHEMBL463600 | 0.84 | AR (0.47) | ALOX5APFEN1ARKIF11ALDH1A1 | |
| SCHEMBL11592825 | 0.82 | CYP1A2 (0.36) | ALOX5APFEN1ARKIF11ALDH1A1 | |
| SCHEMBL3583832 | 0.81 | KDM4E (0.49) | ARKIF11ALDH1A1KDM4ETSHR | |
| SCHEMBL29938879 | 0.81 | AR (0.49) | ARKIF11MAPTL3MBTL1 | |
| SCHEMBL29546917 | 0.81 | AR (0.52) | ARKIF11PTPN1PTPN6PTPN11 | |
| SCHEMBL12151755 | 0.81 | AR (0.52) | ARKIF11PTPN1PTPN6PTPN11 | |
| SCHEMBL2432042 | 0.80 | ALDH1A1 (0.42) | KIF11ALDH1A1KDM4EHSD17B10PKM | |
| SCHEMBL165967 | 0.80 | ALDH1A1 (0.47) | ARKIF11ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108640919-B | Matrine derivative and sophoridine derivative containing aryl amidine or aminoquinoline structure and preparation method thereof | 广西大学 | 2020-09-08 | — | — | CN | claimed |
| US-20250171417-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2025-05-29 | — | — | US | disclosed |
| US-12258354-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2025-03-25 | — | — | US | disclosed |
| EP-3749669-B3 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-118496491-A | Amino acid derived mimic enzyme organic catalyst and application thereof | 青岛科技大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-118373980-A | Preparation method and application of polyether guanidine compound | 青岛科技大学 | 2024-07-23 | — | — | CN | disclosed |
| WO-2024126619-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING A COMPOUND OF FORMULA (I) AND A COMPOUND OF FORMULA (II), AND DISPLAY DEVICE COMPRISING THE ORGANIC ELECTROLUMINESCENT DEVICE | NOVALED GMBH (DE) | 2024-06-20 | — | — | WO | disclosed |
| EP-4385985-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-06-19 | — | — | EP | disclosed |
| CN-111683950-B | AhR modulators | 伊迪亚生物科学有限公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2024061807-A1 | ORGANIC ELECTRONIC DEVICE COMPRISING A CHARGE GENERATION LAYER | NOVALED GMBH (DE) | 2024-03-28 | — | — | WO | disclosed |
| US-6175041-B1 | HYDROGENATING A TRIFLUOROMETHYLBENZONITRILE WITH HYDROGEN IN AN ORGANIC SOLVENT IN THE PRESENCE OF AMMONIA, USING A RANEY CATALYST | CENTRAL GLASS COMPANY, LIMITED (JP) | 2001-01-16 | — | — | US | disclosed |
| WO-2000029398-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-05-25 | — | — | WO | disclosed |
| US-5109004-A | Cyano phenyl-substituted with heterocylic compound; insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-28 | — | — | US | disclosed |
| US-5079251-A | Insecticides, pesticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-07 | — | — | US | disclosed |
| EP-0408196-A2 | Pyrazinone derivatives as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-16 | — | — | EP | disclosed |
| EP-0398499-A2 | Insecticides | ZENECA LIMITED (GB) | 1990-11-22 | — | — | EP | disclosed |
| US-4293566-A | FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| US-4183949-A | Pesticidally active 1-arylamino-2,4-dinitronaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-15 | — | — | US | disclosed |
| US-4059402-A | SUBLIMATION, MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |
| US-3976633-A | ANORECTIC, ANTIOBESITY | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12258354-B2 | AhR modulators | AHR, ARNT, RORB | ALOX5AP 1111/4885FEN1 4852/4885AR 77/4885 |
| US-20250171417-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | AR, BCKDK, CYP11B2 | ALOX5AP 2578/4885FEN1 4870/4885AR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.