Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780932 | 0.85 | KIF11 (0.55) | ARALDH1A1KDM4EHSD17B10KIF11 | |
| SCHEMBL29646422 | 0.84 | ALOX5AP (0.44) | ARALDH1A1KDM4EHSD17B10PKM | |
| SCHEMBL165877 | 0.84 | ALOX5AP (0.44) | ARALDH1A1KDM4EHSD17B10PKM | |
| SCHEMBL24749621 | 0.81 | AR (0.52) | ARL3MBTL1MAPTRAB9ALMNA | |
| SCHEMBL30768289 | 0.81 | AR (0.52) | ARL3MBTL1MAPTRAB9ALMNA | |
| SCHEMBL29546917 | 0.81 | AR (0.52) | ARKIF11TAS2R14CYP11B1CYP11B2 | |
| SCHEMBL12151755 | 0.81 | AR (0.52) | ARKIF11TAS2R14CYP11B1CYP11B2 | |
| SCHEMBL8969267 | 0.80 | ALDH1A1 (0.52) | ARALDH1A1KDM4EHSD17B10PKM | |
| SCHEMBL17782865 | 0.78 | AR (0.49) | ARKIF11TAS2R14CYP11B1CYP11B2 | |
| SCHEMBL495426 | 0.78 | CYP11B1 (0.57) | ARKIF11TAS2R14ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106946800-A | A kind of synthetic method of (1H, the 3H) diketone of quinazoline 2,4 and its derivative | 华东师范大学 | 2017-07-14 | — | — | CN | claimed |
| CN-101565369-B | Method for preparing 3-bromine-5-trifluoromethylbenzoic acid | JIANGSU KAIYUAN PHARMACEUTICAL CHEMICAL ENGINEERING CO LTD | 2012-10-03 | — | — | CN | claimed |
| US-20250221979-A1 | NOVEL HETEROCYCLIC COMPOUND | SHOUYAO HOLDINGS BEIJING CO LTD (CN) | 2025-07-10 | — | — | US | disclosed |
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| US-12257243-B2 | 5-hydroxy-7-oxabicyclo[2.2.1]heptane-2-carboxamide derivatives for inducing chondrogenesis for treating joint damage | NOVARTIS AG (CH) | 2025-03-25 | — | — | US | disclosed |
| EP-4501912-A1 | NOVEL HETEROCYCLIC COMPOUND | Shouyao Holdings (Beijing) Co., Ltd. (CN) | 2025-02-05 | — | — | EP | disclosed |
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-118475560-A | Novel heterocyclic compound | 首药控股(北京)股份有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-118324761-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-113015735-B | 5-Hydroxy-7-oxabicyclo [2.2.1] heptane-2-carboxamide derivatives for inducing chondrogenesis for the treatment of joint damage | 诺华股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118108627-A | Hydrogenation method for breaking fluorocarbon bonds of trifluoromethyl aromatic hydrocarbon | 中国科学院大连化学物理研究所 | 2024-05-31 | — | — | CN | disclosed |
| US-5037833-A | Anticholinergic agents; alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-06 | — | — | US | disclosed |
| US-5002955-A | Pyrroloquinolines for enhancement of memory | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4843079-A | ALZHEIMER*S DISEASE | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0306826-A1 | N-(substituted alkylidene)fused bicycloalkylidene and hetero-alkylidene quinolinamines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-03-15 | — | — | EP | disclosed |
| EP-0287977-A2 | Fused heteroalkylene quinolinamines, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-10-26 | — | — | EP | disclosed |
| EP-0280156-A2 | Process for the preparation of acetoacetylarylamides-heteroarylamides respectively of deactived aromatic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-31 | — | — | EP | disclosed |
| US-3987192-A | ANTIALLERGENS AND ANTIANAPHYLAXID; 2'-CYANO-OXANILIC ACID | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-RE28939-E | MUSCLE RELAXANTS, ANALGESICS | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3976633-A | ANORECTIC, ANTIOBESITY | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250221979-A1 | NOVEL HETEROCYCLIC COMPOUND | MAPT, MNAT1, MAT2A | AR 1962/4885ALDH1A1 996/4885KDM4E 3698/4885 |
| US-12257243-B2 | 5-hydroxy-7-oxabicyclo[2.2.1]heptane-2-carboxamide derivatives for inducing chondrogenesis for treating joint damage | COL2A1, COL1A1, FGF1 | AR 1318/4885ALDH1A1 8/4885KDM4E 1556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.