Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Quercetin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 10/20 | 1.00 |
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.97 |
| ▸ | HDAC6 known ✓ | Q9UBN7 | 4/20 | 0.97 |
| ▸ | DPP4 known ✓ | P27487 | 3/20 | 0.97 |
| ▸ | FLT3 known ✓ | P36888 | 3/20 | 0.97 |
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.97 |
| ▸ | SYK known ✓ | P43405 | 3/20 | 0.97 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 3/20 | 0.97 |
| ▸ | ALOX5 known ✓ | P09917 | 2/20 | 0.97 |
| ▸ | GSK3A known ✓ | P49840 | 2/20 | 0.97 |
| ▸ | GSK3B known ✓ | P49841 | 2/20 | 0.97 |
| ▸ | PIK3CG known ✓ | P48736 | 2/20 | 0.97 |
| ▸ | MMP1 known ✓ | P03956 | 2/20 | 0.97 |
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.97 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.97 |
| ▸ | MET known ✓ | P08581 | 1/20 | 0.97 |
| ▸ | DRD4 known ✓ | P21917 | 1/20 | 0.97 |
| ▸ | CXCR1 known ✓ | P25024 | 1/20 | 0.97 |
| ▸ | PIK3R1 known ✓ | P27986 | 1/20 | 0.97 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quercetin SCHEMBL29695492 | 1.00 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4KDM4E | |
| Quercetin SCHEMBL22103 | 1.00 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4KDM4E | |
| Quercetin SCHEMBL29597013 | 1.00 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4KDM4E | |
| Quercetin SCHEMBL29738299 | 1.00 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4KDM4E | |
| Quercetin SCHEMBL28067078 | 1.00 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4KDM4E | |
| Quercetin SCHEMBL29449339 | 0.99 | MEN1 (0.97) | MEN1KMT2ACYP1A2CYP3A4KDM4E | |
| Quercetin SCHEMBL118425 | 0.99 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4KDM4E | |
| Quercetin SCHEMBL29351036 | 0.99 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4KDM4E | |
| Quercetin SCHEMBL19723 | 0.99 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4KDM4E | |
| Quercetin SCHEMBL17629824 | 0.99 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619940-A | Berberine hydrochloride-quercetin hydrate eutectic crystal and preparation method and application thereof | 闽江学院 | 2024-09-10 | — | — | CN | claimed |
| US-11351145-B2 | Quercetin-based composition for treating rhinosinusitis | APHABIO THERAPEUTICS (FR) | 2022-06-07 | — | — | US | claimed |
| CN-113304113-A | Co-amorphous solid dispersion for improving dissolution of quercetin and preparation method thereof | 桂林医学院 | 2021-08-27 | — | — | CN | claimed |
| US-20210000787-A1 | QUERCETIN-BASED COMPOSITION FOR TREATING RHINOSINUSITIS | APHABIO THERAPEUTICS (FR) | 2021-01-07 | — | — | US | claimed |
| US-20200289525-A1 | Methods of Increasing Microbial Diversity of a Skin Microbiota | THE PROCTER & GAMBLE COMPANY | 2020-09-17 | — | — | US | claimed |
| CN-111615384-A | Method for treating sinusitis | 阿法比奥治疗公司 | 2020-09-01 | — | — | CN | claimed |
| CN-110951670-A | Cell culture compositions with antioxidants and methods of polypeptide production | 豪夫迈·罗氏有限公司 | 2020-04-03 | — | — | CN | claimed |
| CN-105121628-B | Cell culture compositions with antioxidants and methods of polypeptide production | 豪夫迈·罗氏有限公司 | 2020-03-24 | — | — | CN | claimed |
| CN-110075103-A | The purposes of Quercetin | 中国科学院动物研究所 | 2019-08-02 | — | — | CN | claimed |
| EP-3277271-A1 | ANTIVIRAL ACTIVITY FROM MEDICINAL MUSHROOMS AND THEIR ACTIVE CONSTITUENTS | Stamets, Paul Edward (US) | 2018-02-07 | — | — | EP | claimed |
| EP-2323613-B1 | COMPOSITE PARTICLES HAVING AN ANTIOXIDANT-BASED PROTECTIVE SYSTEM, AND TOPICAL COMPOSITIONS COMPRISING THE SAME | ELC MAN LLC (US) | 2016-11-30 | — | — | EP | claimed |
| WO-2016161138-A1 | ANTIVIRAL ACTIVITY FROM MEDICINAL MUSHROOMS AND THEIR ACTIVE CONSTITUENTS | STAMETS PAUL EDWARD (US) | 2016-10-06 | — | — | WO | claimed |
| US-20160000754-A1 | Antiviral Activity from Medicinal Mushrooms and their Active Constituents | TURTLE BEAR HOLDINGS, LLC | 2016-01-07 | — | — | US | claimed |
| EP-2323613-A2 | COMPOSITE PARTICLES HAVING AN ANTIOXIDANT-BASED PROTECTIVE SYSTEM, AND TOPICAL COMPOSITIONS COMPRISING THE SAME | ELC Management LLC (US) | 2011-05-25 | — | — | EP | claimed |
| WO-2010019413-A2 | COMPOSITE PARTICLES HAVING AN ANTIOXIDANT-BASED PROTECTIVE SYSTEM, AND TOPICAL COMPOSITIONS COMPRISING THE SAME | ELC MANAGEMENT LLC (US) | 2010-02-18 | — | — | WO | claimed |
| US-20100040696-A1 | Composite Particles Having An Antioxidant-Based Protective System, And Topical Compositions Comprising The Same | ELC MANAGEMENT LLC | 2010-02-18 | — | — | US | claimed |
| US-12516034-B2 | Process for preparing high-density quercetin | TRADICHEM INDUSTRIAL SERVICES, S.L. (ES) | 2026-01-06 | — | — | US | disclosed |
| EP-4641300-A1 | COMPOSITION FOR FORMING RESIST UNDERLAYER FILM TO REDUCE ENVIRONMENTAL IMPACT | Nissan Chemical Corporation (JP) | 2025-10-29 | — | — | EP | disclosed |
| WO-2010019413-A2 | COMPOSITE PARTICLES HAVING AN ANTIOXIDANT-BASED PROTECTIVE SYSTEM, AND TOPICAL COMPOSITIONS COMPRISING THE SAME | ELC MANAGEMENT LLC (US) | 2010-02-18 | — | — | WO | disclosed |
| US-20100040696-A1 | Composite Particles Having An Antioxidant-Based Protective System, And Topical Compositions Comprising The Same | ELC MANAGEMENT LLC | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000754-A1 | Antiviral Activity from Medicinal Mushrooms and their Active Constituents | MAVS, STING1, ZC3HAV1 | MEN1 207/4885ACHE 178/4885HDAC6 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.