Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571218 | 0.86 | KMT2A (0.57) | NAAAHPGDALDH1A1CYP2C9KDM4E | |
| SCHEMBL7542456 | 0.86 | NAAA (0.63) | NAAAHPGDCASP2MAPTTDP1 | |
| SCHEMBL4086405 | 0.84 | HDAC1 (0.58) | NAAAHPGDCYP2C9MAPTSMN1; SMN2 | |
| SCHEMBL1002638 | 0.81 | NAAA (1.00) | NAAAEPHX1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1003239 | 0.81 | NAAA (1.00) | NAAAEPHX1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8204741 | 0.81 | NAAA (1.00) | NAAAEPHX1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1004555 | 0.81 | NAAA (1.00) | NAAAEPHX1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1002305 | 0.81 | NAAA (1.00) | NAAAEPHX1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL421014 | 0.81 | NAAA (1.00) | NAAAEPHX1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL20216434 | 0.81 | NAAA (1.00) | NAAAEPHX1ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366561-A1 | SYSTEM AND ASSAY FOR MONITORING PRODUCTION/RELEASE OF MEMBRANE-LYTIC TOXINS IN BACTERIA AND COMPOUNDS FOR MODULATING SAME | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2024-11-07 | — | — | US | disclosed |
| US-12070445-B2 | System and assay for monitoring production/release of membrane-lytic toxins in bacteria and compounds for modulating same | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2024-08-27 | — | — | US | disclosed |
| CN-117965525-A | Method for screening bacterial quorum sensing signal inhibitor | 清华大学深圳国际研究生院 | 2024-05-03 | — | — | CN | disclosed |
| US-20230070337-A1 | SYSTEM AND ASSAY FOR MONITORING PRODUCTION/RELEASE OF MEMBRANE-LYTIC TOXINS IN BACTERIA AND COMPOUNDS FOR MODULATING SAME | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2023-03-09 | — | — | US | disclosed |
| US-10751495-B2 | Patient interface | KONINKLIJKE PHILIPS N.V. (NL) | 2020-08-25 | — | — | US | disclosed |
| US-9751851-B2 | Molecules and compositions that inhibit gram negative bacteria and their uses | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| US-9751851-B2 | Molecules and compositions that inhibit gram negative bacteria and their uses | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| US-20160368892-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160368892-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160317771-A1 | PATIENT INTERFACE | KONINKLIJKE PHILIPS N.V. | 2016-11-03 | — | — | US | disclosed |
| WO-2015042363-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230070337-A1 | SYSTEM AND ASSAY FOR MONITORING PRODUCTION/RELEASE OF MEMBRANE-LYTIC TOXINS IN BACTERIA AND COMPOUNDS FOR MODULATING SAME | LIPE, LYPLA2, LYPLA1 | NAAA 283/4885HPGD 2942/4885EPHX1 1223/4885 |
| US-20240366561-A1 | SYSTEM AND ASSAY FOR MONITORING PRODUCTION/RELEASE OF MEMBRANE-LYTIC TOXINS IN BACTERIA AND COMPOUNDS FOR MODULATING SAME | LIPE, LYPLA2, LYPLA1 | NAAA 283/4885HPGD 2942/4885EPHX1 1223/4885 |
| US-20160368892-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | BLVRB, PGLS, GRHPR | NAAA 1374/4885HPGD 481/4885EPHX1 2628/4885 |
| US-12070445-B2 | System and assay for monitoring production/release of membrane-lytic toxins in bacteria and compounds for modulating same | LIPE, LYPLA2, LYPLA1 | NAAA 283/4885HPGD 2942/4885EPHX1 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.