Gluconic Acid

Gluconic Acid

SCHEMBL16609880

O=C(O)[C@H](O)[C@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHESCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A

The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PDE4A P27815 1/20 1.00
▸ LMNA P02545 2/20 0.67
▸ USP2 O75604 1/20 0.60
▸ SLCO1B1 Q9Y6L6 1/20 0.60
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ TDP1 Q9NUW8 1/20 0.55
▸ TSHR P16473 2/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ OR51E2 Q9H255 1/20 0.43
▸ KDM4E B2RXH2 2/20 0.41
▸ PGD P52209 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gluconic Acid SCHEMBL147940 1.00 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Mucic Acid SCHEMBL7527588 1.00 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Mucic Acid SCHEMBL7538629 1.00 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL8465565 1.00 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL16609822 1.00 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL433662 1.00 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL338748 1.00 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL338310 1.00 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL21778048 1.00 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL16609840 1.00 PDE4A (1.00) PDE4ALMNAUSP2SLCO1B1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025263641-A1 COMPOSITION COMPRISING GLYCOLIPID, CATIONIC POLYMER AND (POLY)HYDROXY ACID L'OREAL (FR) 2025-12-26 — — WO claimed
EP-4608352-A1 AQUEOUS MAKE-UP-REMOVING COMPOSITION HAVING A MILD PEELING EFFECT L'OREAL (FR) 2025-09-03 — — EP claimed
US-12122745-B2 Processes for preparing aldaric, aldonic, and uronic acids ARCHER-DANIELS-MIDLAND COMPANY (US) 2024-10-22 — — US claimed
WO-2024088996-A1 AQUEOUS MAKE-UP-REMOVING COMPOSITION HAVING A MILD PEELING EFFECT L'OREAL (FR) 2024-05-02 — — WO claimed
CN-117229272-A Preparation method of enggliflozin 安徽美诺华药物化学有限公司 2023-12-15 — — CN claimed
US-20230028813-A1 PROCESSES FOR PREPARING ALDARIC, ALDONIC, AND URONIC ACIDS ARCHER DANIELS MIDLAND CO (US) 2023-01-26 — — US claimed
EP-4112594-A1 PROCESSES FOR PREPARING ALDARIC, ALDONIC, AND URONIC ACIDS Archer-Daniels-Midland Company (US) 2023-01-04 — — EP claimed
EP-3822247-B1 PROCESSES FOR PREPARING ALDARIC, ALDONIC, AND URONIC ACIDS ARCHER DANIELS MIDLAND CO (US) 2022-06-08 — — EP claimed
EP-3997164-A1 USE OF PHENOLICALLY SUBSTITUTED SUGAR DERIVATIVES AS STABILISERS, PLASTIC COMPOSITION, METHOD FOR STABILISING PLASTICS AND PHENOLICALLY SUBSTITUTED SUGAR DERIVATIVES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-05-18 — — EP claimed
US-20260144811-A1 HYDROGEL FOR BODY CAVITY INJURY TREATMENT AND BODY CAVITY INJURY TREATMENT KIT KAGOSHIMA UNIVERSITY (JP) 2026-05-28 — — US disclosed
CN-122055127-A Composition for caring keratin materials 莱雅公司 2026-05-15 — — CN disclosed
CN-122055126-A Leave-on composition for caring for keratin materials 莱雅公司 2026-05-15 — — CN disclosed
EP-4740936-A1 HYDROGEL FOR BODY CAVITY INJURY TREATMENT AND BODY CAVITY INJURY TREATMENT KIT Kagoshima University (JP) 2026-05-13 — — EP disclosed
US-12552913-B2 Use of phenolically substituted sugar derivatives as stabilisers, plastic composition, method for stabilising plastics and phenolically substituted sugar derivatives Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2026-02-17 — — US disclosed
US-10456481-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo HERCULES CAPITAL, INC. 2019-10-29 — — US disclosed
US-20160235863-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2016-08-18 — — US disclosed
US-20160235863-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2016-08-18 — — US disclosed
US-9044733-B2 Method and apparatus for preparing a solution of a shear sensitive material OTSUKA AMERICA PHARMACEUTICAL, INC. (US) 2015-06-02 — — US disclosed
US-9034256-B2 Method and apparatus for preparing a solution of shear sensitive material OTSUKA AMERICA PHARMACEUTICAL, INC. (US) 2015-05-19 — — US disclosed
WO-2015042711-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO ENGENE, INC. (CA) 2015-04-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144811-A1 HYDROGEL FOR BODY CAVITY INJURY TREATMENT AND BODY CAVITY INJURY TREATMENT KIT CUTA, AADAT, OGA PDE4A 3876/4885LMNA 105/4885USP2 2582/4885
US-20230028813-A1 PROCESSES FOR PREPARING ALDARIC, ALDONIC, AND URONIC ACIDS ALDOA, AKR1C4, ADSL PDE4A 3856/4885LMNA 645/4885USP2 650/4885
US-12552913-B2 Use of phenolically substituted sugar derivatives as stabilisers, plastic composition, method for stabilising plastics and phenolically substituted sugar derivatives SORD, GYS1, GYS2 PDE4A 4863/4885LMNA 1993/4885USP2 4586/4885
US-12122745-B2 Processes for preparing aldaric, aldonic, and uronic acids ALDOA, AKR1C4, ADSL PDE4A 3856/4885LMNA 645/4885USP2 650/4885
US-10456481-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo CSGALNACT1, CHI3L2, LNPEP PDE4A 4587/4885LMNA 1219/4885USP2 615/4885
US-20160235863-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP PDE4A 4587/4885LMNA 1219/4885USP2 615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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