Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16640636 | 0.88 | TSHR (0.43) | MAPK14ALDH1A1GAAKMT2AL3MBTL1 | |
| SCHEMBL16411434 | 0.85 | NOTUM (0.62) | NOTUMPTGER1TEAD3ALDH1A1GAA | |
| SCHEMBL19646277 | 0.84 | HTT (0.42) | NOTUMMAPK14TEAD3ALDH1A1GAA | |
| SCHEMBL29886703 | 0.80 | NOTUM (0.45) | NOTUMTEAD3ALDH1A1GAAMEN1 | |
| SCHEMBL16640630 | 0.79 | KMT2A (0.44) | NOTUMMAPK14TEAD3ALDH1A1GAA | |
| SCHEMBL19646278 | 0.78 | ALDH1A1 (0.43) | MAPK14ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL16415457 | 0.76 | TSHR (0.48) | NOTUMALDH1A1GAAPKMMEN1 | |
| SCHEMBL12584099 | 0.75 | ALDH1A1 (0.42) | NOTUMPTGER1TEAD3ALDH1A1GAA | |
| SCHEMBL20661083 | 0.74 | TEAD3 (0.45) | TEAD3ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL27199304 | 0.73 | L3MBTL1 (0.39) | MAPK14TEAD3GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9827336-B2 | Radio-pharmaceutical complexes | BAYER AS (NO) | 2017-11-28 | — | — | US | disclosed |
| US-20150147272-A1 | RADIO-PHARMACEUTICAL COMPLEXES | BAYER AS (NO) | 2015-05-28 | — | — | US | disclosed |
| US-20150110817-A1 | RADIO-PHARMACEUTICAL COMPLEXES | BAYER AS (NO) | 2015-04-23 | — | — | US | disclosed |
| US-20150104385-A1 | RADIO-PHARMACEUTICAL COMPLEXES | ALGETA ASA (NO) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150147272-A1 | RADIO-PHARMACEUTICAL COMPLEXES | HCAR3, TYRO3, HCAR1 | NOTUM 3567/4885MAPK14 4656/4885PTGER1 3082/4885 |
| US-20150104385-A1 | RADIO-PHARMACEUTICAL COMPLEXES | CD22, HAVCR2, CD2 | NOTUM 3042/4885MAPK14 4708/4885PTGER1 3578/4885 |
| US-20150110817-A1 | RADIO-PHARMACEUTICAL COMPLEXES | TSPO, TK1, HCAR1 | NOTUM 2991/4885MAPK14 4737/4885PTGER1 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.