Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16640636 | 0.79 | TSHR (0.43) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL29220666 | 0.74 | CRHBP (0.43) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL16415457 | 0.72 | TSHR (0.48) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL19646278 | 0.72 | ALDH1A1 (0.43) | MAPTSMN1; SMN2NPC1KMT2AKDM4E | |
| SCHEMBL16748374 | 0.71 | BAZ2B (0.41) | MAPTSMN1; SMN2KDM4ELMNAGAA | |
| SCHEMBL16640634 | 0.71 | NOTUM (0.48) | MAPTSMN1; SMN2KMT2AGAAPKM | |
| SCHEMBL16640631 | 0.71 | BRD4 (0.47) | SMN1; SMN2KMT2ALMNAPKMALDH1A1 | |
| SCHEMBL20660562 | 0.70 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL4236522 | 0.68 | ALDH1A1 (0.44) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL2791982 | 0.68 | LMNA (0.40) | MAPTSMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150147272-A1 | RADIO-PHARMACEUTICAL COMPLEXES | BAYER AS (NO) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150147272-A1 | RADIO-PHARMACEUTICAL COMPLEXES | HCAR3, TYRO3, HCAR1 | MAPT 3550/4885SMN1; SMN2 4815/4885NPC1 1718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.