SCHEMBL166427

SCHEMBL166427

c1ccc(Pc2ccccc2Oc2ccccc2Pc2ccccc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.32
TSHR P16473 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
HTT P42858 1/20 0.31
NR1H2 P55055 1/20 0.30
BAX Q07812 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27660156 0.87 MMP3 (0.38) CA1CA2
SCHEMBL3670294 0.83 NCOA1 (0.34)
SCHEMBL19719371 0.82 HPGD (0.44) TSHR
SCHEMBL21134100 0.82 ALDH1A1 (0.32)
SCHEMBL18053430 0.82 CYP3A4 (0.34)
SCHEMBL4444463 0.82 CA1 (0.50) TSHRCA12CA1CA2CA4
SCHEMBL30810811 0.82 CA1 (0.50) TSHRCA12CA1CA2CA4
SCHEMBL4888931 0.80 CA1 (0.48) TSHRCA12CA1CA2CA4
Hydrochloric Acid SCHEMBL2154353 0.80 CA1 (0.48) TSHRCA12CA1CA2CA4
SCHEMBL28379424 0.80 CA1 (0.48) TSHRCA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114409699-B Novel X-ray luminescent material and preparation method thereof 南京邮电大学 2023-10-20 CN claimed
CN-114409699-A Novel X-ray luminescent material and preparation method thereof 南京邮电大学 2022-04-29 CN claimed
US-12595247-B2 Substituted pyrazolo piperidine carboxylic acids BAYER AKTIENGESELLSCHAFT (DE) 2026-04-07 US disclosed
US-20250026737-A1 SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS BAYER AG (DE) 2025-01-23 US disclosed
US-12195448-B2 Substituted pyrazolo piperidine carboxylic acids BAYER AKTIENGESELLSCHAFT (DE) 2025-01-14 US disclosed
US-12064429-B2 Substituted 5-fluoro-1H-pyrazolopyridines and their use ADVERIO PHARMA GMBH (DE) 2024-08-20 US disclosed
US-20240109864-A1 SUBSTITUTED PYRAZOLYL PIPERIDINE CARBOXYLIC ACIDS BAYER AKTIENGESELLSCHAFT (DE) 2024-04-04 US disclosed
US-20240101528-A1 SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS BAYER AKTIENGESELLSCHAFT (DE) 2024-03-28 US disclosed
EP-3455224-B1 SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF BAYER AG (DE) 2024-03-27 EP disclosed
US-20240051935-A1 SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS BAYER AKTIENGESELLSCHAFT (DE) 2024-02-15 US disclosed
US-20230346777-A1 USE OF SGC ACTIVATORS FOR THE TREATMENT OF OPHTHALMOLOGIC DISEASES BAYER AG (DE) 2023-11-02 US disclosed
EP-2385942-A1 BENZIMIDAZOLE AND PYRAZOLOPYRIDINE DERIVATIVES FOR TREATING AND/OR PREVENTING CARDIOVASCULAR DISEASES Bayer Pharma Aktiengesellschaft (DE) 2011-11-16 EP disclosed
US-20110254572-A1 CAPACITANCE-TYPE SENSOR FUJIKURA LTD. (JP) 2011-10-20 US disclosed
CN-102197031-A Substituted 5-aminopyrazoles and use thereof BAYER SCHERING PHARMA AG 2011-09-21 CN disclosed
EP-2321296-A1 SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF Bayer Schering Pharma Aktiengesellschaft (DE) 2011-05-18 EP disclosed
WO-2010079120-A1 BENZIMIDAZOLE AND PYRAZOLOPYRIDINE DERIVATIVES FOR TREATING AND/OR PREVENTING CARDIOVASCULAR DISEASES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-07-15 WO disclosed
US-20100099681-A1 SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-04-22 US disclosed
WO-2010020366-A1 AZABICYCLIC SUBSTITUTED 5-AMINOPYRAZOLES AND THE USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-02-25 WO disclosed
WO-2010020363-A1 SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-02-25 WO disclosed
CN-101119747-A Tissue factor production inhibitor SANKYO CO (JP) 2008-02-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12064429-B2 Substituted 5-fluoro-1H-pyrazolopyridines and their use PFKP, PON1, FABP3 LTA4H 2617/4885TSHR 2505/4885CA12 4874/4885
US-20240051935-A1 SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS PLOD3, PDK4, PDF LTA4H 2416/4885TSHR 4041/4885CA12 4823/4885
US-12195448-B2 Substituted pyrazolo piperidine carboxylic acids PLOD3, PDK4, PDF LTA4H 2416/4885TSHR 4041/4885CA12 4823/4885
US-20240109864-A1 SUBSTITUTED PYRAZOLYL PIPERIDINE CARBOXYLIC ACIDS PLOD3, PDK4, PDF LTA4H 2383/4885TSHR 4099/4885CA12 4815/4885
US-20230346777-A1 USE OF SGC ACTIVATORS FOR THE TREATMENT OF OPHTHALMOLOGIC DISEASES PRKG1, PGC, PRKG2 LTA4H 2852/4885TSHR 696/4885CA12 4795/4885
US-12595247-B2 Substituted pyrazolo piperidine carboxylic acids SSB, PDK4, FPR1 LTA4H 2694/4885TSHR 2440/4885CA12 4765/4885
US-20100099681-A1 SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF CYP3A5, ABAT, TPMT LTA4H 1019/4885TSHR 3887/4885CA12 4470/4885
US-20240101528-A1 SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS PLOD3, PDK4, PDF LTA4H 2416/4885TSHR 4041/4885CA12 4823/4885
US-20250026737-A1 SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS PLOD3, PDK4, PDF LTA4H 2416/4885TSHR 4041/4885CA12 4823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.