Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16663581 | 0.82 | ALDH1A1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL4320538 | 0.79 | ACLY (0.37) | ALDH1A1HDAC4HDAC6 | |
| SCHEMBL16658461 | 0.78 | CYP4F2 (0.39) | TSHRALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL16658462 | 0.78 | DGAT1 (0.34) | ALDH1A1LMNA | |
| SCHEMBL9017248 | 0.73 | — | — | |
| SCHEMBL7942800 | 0.71 | — | — | |
| SCHEMBL11185102 | 0.71 | — | — | |
| SCHEMBL26380 | 0.70 | ALDH1A1 (0.38) | TSHRALDH1A1LMNACYP2D6CYP2C19 | |
| SCHEMBL5947966 | 0.70 | ALDH1A1 (0.38) | TSHRALDH1A1LMNACYP2D6CYP2C19 | |
| SCHEMBL642729 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150112095-A1 | PARTIALLY FLUORINATED ALCOHOLS AND DERIVATIVES | E I DU PONT DE NEMOURS AND COMPANY (DE) | 2015-04-23 | — | — | US | disclosed |
| US-20150112036-A1 | PARTIALLY FLUORINATED POLYMERS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150112095-A1 | PARTIALLY FLUORINATED ALCOHOLS AND DERIVATIVES | ADH1C, ADH1A, AFF1 | TSHR 641/4885ALDH1A1 126/4885LMNA 1547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.