SCHEMBL26380

SCHEMBL26380

CCOC(C)(OCC)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
FFAR3 O14843 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ACLY P53396 1/20 0.32
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27636970 0.97 ALDH1A1 (0.36) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL7760442 0.89 HCAR2 (0.36) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL4471217 0.87 TSHR (0.33) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL9937133 0.85 HTT (0.33)
SCHEMBL9134539 0.82 MAPT (0.37) ACACBACACA
SCHEMBL30622145 0.82 ACACB (0.31) ACACBACACA
SCHEMBL30601277 0.82 MAPT (0.33) ALDH1A1ACLYHCAR2
SCHEMBL27503093 0.80 RXRA (0.43) ALDH1A1HSD17B10ALOX15GAA
SCHEMBL29209620 0.79 ALDH1A1 (0.35) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL30914641 0.79 CYP4F2 (0.31) CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113582915-B Synthesis method of 4-substituted pyridine compound 河南师范大学 2024-03-08 CN claimed
CN-113582915-A Synthesis method of 4-substituted pyridine compound 河南师范大学 2021-11-02 CN claimed
EP-2482996-B1 METHOD FOR THE SPOT REPAIR OF SCRATCH-RESISTANT PAINT FILMS BASF COATINGS GMBH (DE) 2016-03-30 EP claimed
EP-1644384-B1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF ENTECAVIR BRISTOL MYERS SQUIBB CO (US) 2012-10-31 EP claimed
EP-1242382-B1 TRICYCLIC PROTEIN KINASE INHIBITORS WYETH CORP (US) 2007-02-07 EP claimed
EP-1140933-B1 PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES AVENTIS PHARMA INC (US) 2004-09-08 EP claimed
EP-0662970-A1 PROCESS FOR THE PREPARATION OF 2-AMINO-6-CHLOROPURINE SMITHKLINE BEECHAM PLC (GB) 1995-07-19 EP claimed
EP-0319228-B1 Novel compounds BEECHAM GROUP PLC (GB) 1994-11-02 EP claimed
WO-1994007892-A1 PROCESS FOR THE PREPARATION OF 2-AMINO-6-CHLOROPURINE SMITHKLINE BEECHAM PLC (GB) 1994-04-14 WO claimed
EP-3946460-B1 IMPROVED CONJUGATION LINKERS PROLYNX LLC (US) 2026-05-20 EP disclosed
US-12600705-B2 Heat shock protein modulators and anti-Huntington disease therapeutic agents UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2026-04-14 US disclosed
US-20260007768-A1 CONJUGATION LINKERS PROLYNX LLC (US) 2026-01-08 US disclosed
US-12364771-B2 Conjugation linkers PROLYNX LLC (US) 2025-07-22 US disclosed
CN-119970617-A Improved coupling joint 普罗林科斯有限责任公司 2025-05-13 CN disclosed
US-4269980-A TRANQUILIZERS; ANTICONVULSANTS AMERICAN CYANAMID COMPANY (US) 1981-05-26 US disclosed
US-4110116-A Fogged direct positive silver halide emulsion containing a cyanine dye having at least one benzoxazole or benzothiazole nucleus substituted with halogen atoms MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-08-29 US disclosed
US-4093812-A MICROBIOCIDES, DISINFECTANTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1978-06-06 US disclosed
US-4034093-A INHIBITION OF XANTHINEOXIDASE BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1977-07-05 US disclosed
US-4003750-A METHINE DYES EASTMAN KODAK COMPANY (US) 1977-01-18 US disclosed
US-3865824-A 2-Aryl-7-substituted pyrazolo {8 1,5{i a{b {9 1,3,5-triazines ICN PHARMACEUTICALS 1975-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600705-B2 Heat shock protein modulators and anti-Huntington disease therapeutic agents HEATR1, HSPH1, HEATR6 ALDH1A1 2856/4885TSHR 380/4885CYP2D6 3513/4885
US-20260007768-A1 CONJUGATION LINKERS OGFR, SLC43A1, ILK ALDH1A1 1312/4885TSHR 31/4885CYP2D6 504/4885
US-12364771-B2 Conjugation linkers DNPEP, FGB, VIP ALDH1A1 1899/4885TSHR 1528/4885CYP2D6 4154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.