Sugi Predict

Sugi Predict / Compounds / SCHEMBL16660726

SCHEMBL16660726

SCHEMBL16660726

Cc1c(C(=O)N(C)c2ccnnc2)cnn1C1CCC(F)(F)CC1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TRPV4 Q9HBA0 1/20 0.40
▸ KMT2A Q03164 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ TEAD1 P28347 1/20 0.34
▸ TEAD4 Q15561 1/20 0.34
▸ TEAD2 Q15562 1/20 0.34
▸ KDM5A P29375 1/20 0.34
▸ KDM4C Q9H3R0 1/20 0.34
▸ KDM5B Q9UGL1 1/20 0.34
▸ KCNJ6 P48051 2/20 0.33
▸ KCNJ5 P48544 2/20 0.33
▸ KCNJ3 P48549 2/20 0.33
▸ PDE9A O76083 11/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16660723 0.88 KMT2A (0.38) TRPV4KMT2AMEN1NPC1RAB9A
SCHEMBL16660728 0.87 KMT2A (0.38) TRPV4KMT2AMEN1NPC1RAB9A
SCHEMBL16973269 0.87 TRPV4 (0.38) TRPV4TEAD1TEAD4TEAD2KDM5A
SCHEMBL15662045 0.85 KMT2A (0.36) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL16660725 0.83 KMT2A (0.35) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL16660724 0.80 KMT2A (0.38) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL16660727 0.79 KMT2A (0.36) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL16660730 0.77 OXTR (0.37) TRPV4
SCHEMBL16654825 0.76 OXTR (0.35) TRPV4
SCHEMBL16654466 0.75 OXTR (0.37) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 479 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2024-07-11 — — US claimed
EP-4346412-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI Industries Ltd. (IN) 2024-04-10 — — EP claimed
CN-117396074-A Fungicidal compositions containing oxadiazole compounds PI工业有限公司 2024-01-12 — — CN claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 — — US claimed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 — — CN claimed
WO-2022249074-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2022-12-01 — — WO claimed
EP-3978504-A1 CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2022-04-06 — — EP claimed
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF BASF SE (DE) 2022-02-17 — — US claimed
EP-3601298-B1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-12-01 — — EP claimed
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests BASF SE (DE) 2021-11-18 — — US claimed
WO-2018202428-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2018-11-08 — — WO claimed
EP-3383183-A1 MIXTURES OF CIS-JASMONE ANDBACILLUS AMYLOLIQUEFACIENS BASF SE (DE) 2018-10-10 — — EP claimed
WO-2018177970-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2018-10-04 — — WO claimed
US-20170238554-A1 Method and Pesticidal Mixtures for Controlling Pentatomidae Pests BASF CORPORATION 2017-08-24 — — US claimed
EP-3206490-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2017-08-23 — — EP claimed
WO-2017137351-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES BASF SE (DE) 2017-08-17 — — WO claimed
EP-3205208-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES BASF SE (DE) 2017-08-16 — — EP claimed
WO-2017093163-A1 MIXTURES OF CIS-JASMONE AND BACILLUS AMYLOLIQUEFACIENS BASF SE (DE) 2017-06-08 — — WO claimed
EP-3111763-A1 PESTICIDAL COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF Agro B.V. (NL) 2017-01-04 — — EP claimed
WO-2016059240-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2016-04-21 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH TRPV4 4590/4885KMT2A 2611/4885MEN1 1988/4885
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS OXA1L, NOX1, NOX3 TRPV4 3555/4885KMT2A 3280/4885MEN1 2968/4885
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF MANBA, CMA1, MTX1 TRPV4 3223/4885KMT2A 2080/4885MEN1 157/4885
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests THOP1, NIT2, DDT TRPV4 1947/4885KMT2A 3738/4885MEN1 1895/4885
US-20170238554-A1 Method and Pesticidal Mixtures for Controlling Pentatomidae Pests CASP9, CASP6, CASP14 TRPV4 2519/4885KMT2A 3269/4885MEN1 1446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.