Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 4/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18065507 | 1.00 | MMEL1 (0.54) | MMEL1LTA4HMEN1KMT2APOLB | |
| SCHEMBL8647455 | 0.87 | KLK5 (0.61) | MMEL1LTA4HKMT2AADORA3ADORA2A | |
| SCHEMBL8647459 | 0.87 | KLK5 (0.61) | MMEL1LTA4HKMT2AADORA3ADORA2A | |
| SCHEMBL7269454 | 0.87 | KLK5 (0.61) | MMEL1LTA4HKMT2AADORA3ADORA2A | |
| SCHEMBL16673151 | 0.85 | MMEL1 (0.45) | MMEL1MEN1KMT2AACECTRB1 | |
| SCHEMBL371906 | 0.84 | ALDH1A1 (0.55) | MMEL1LTA4HPOLBADORA3ADORA2A | |
| SCHEMBL378574 | 0.84 | ALDH1A1 (0.55) | MMEL1LTA4HPOLBADORA3ADORA2A | |
| SCHEMBL7329010 | 0.81 | ADORA3 (0.58) | MMEL1POLBADORA3ADORA2AADORA2B | |
| SCHEMBL8648992 | 0.81 | ADORA3 (0.58) | MMEL1POLBADORA3ADORA2AADORA2B | |
| SCHEMBL8648996 | 0.81 | ADORA3 (0.58) | MMEL1POLBADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9878975-B2 | Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-20160272571-A1 | Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides | EVONIK DEGUSSA GMBH (DE) | 2016-09-22 | — | — | US | disclosed |
| WO-2015067450-A1 | CATALYTIC HYDROGENATION FOR PRODUCING AMINES FROM CARBOXYLIC ACID AMIDES, CARBOXYLIC ACID DIAMIDES, DI-, TRI-, OR POLYPEPETIDES, OR PEPTIDE AMIDES | EVONIK INDUSTRIES AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| EP-2868643-A1 | Catalytic hydrogenation for the preparation of amines from carboxylic acid amides, carboxylic acid amides, di-, tri- or polypeptides or peptide amides | Evonik Industries AG (DE) | 2015-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272571-A1 | Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides | DAO, DDC, HDGF | MMEL1 2061/4885LTA4H 4674/4885MEN1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.