Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 2/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLR1A | O95602 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735667 | 0.83 | POLB (0.51) | RXFP1POLB | |
| SCHEMBL16735670 | 0.81 | MAPT (0.55) | RXFP1POLBLMNA | |
| SCHEMBL16735647 | 0.81 | POLB (0.49) | RXFP1POLBLMNA | |
| SCHEMBL16735634 | 0.80 | KDM4C (0.54) | RXFP1POLB | |
| SCHEMBL2143867 | 0.79 | ALDH1A1 (0.49) | HRH3MAP4K4ATRL3MBTL3HCRTR1 | |
| SCHEMBL16735593 | 0.79 | RXFP1 (0.56) | RXFP1POLBHCRTR1HCRTR2 | |
| SCHEMBL16735578 | 0.79 | POLB (0.56) | RXFP1POLBLMNA | |
| SCHEMBL16735639 | 0.78 | RXFP1 (0.46) | RXFP1POLBLMNAHCRTR1HCRTR2 | |
| SCHEMBL16735605 | 0.78 | POLB (0.51) | RXFP1POLB | |
| SCHEMBL16735678 | 0.77 | POLR1A (0.51) | HRH3MAP4K4POLR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |