SCHEMBL1680419

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680659	0.82	ALDH1A1 (0.51)	ALDH1A1LMNAALOX5
	SCHEMBL1680731	0.81	LMNA (0.48)	ALDH1A1MAPTSMN1; SMN2NPSR1MEN1
	SCHEMBL14114873	0.78	PARP15 (0.41)	MAOBALDH1A1MAPTMEN1KMT2A
	SCHEMBL9078510	0.78	ALOX5 (0.36)	ALDH1A1SMN1; SMN2LMNAALOX5GAA
	SCHEMBL4743822	0.78	ALDH1A3 (0.51)	ALDH1A1MAPTSMN1; SMN2HSD17B10KMT2A
	SCHEMBL3086894	0.77	HSPB1 (0.47)	ALDH1A1MAPTNPSR1MEN1KMT2A
	SCHEMBL4967487	0.77	PARP10 (0.57)	ALDH1A1KMT2AALOX5
	SCHEMBL25055322	0.76	ALDH1A1 (0.41)	ALDH1A1MAPTALOX5TSHR
	Phenol SCHEMBL9228945	0.75	LTA4H (0.44)	ALDH1A1MAPTSMN1; SMN2NPSR1MEN1
	SCHEMBL25222126	0.72	ALDH1A1 (0.42)	ALDH1A1MAPTSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.