SCHEMBL1680499

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680744	0.83	NPC1 (0.42)	TAAR1MEN1KMT2ACARM1PRMT6
	SCHEMBL1680485	0.82	ALOX5 (0.36)	TAAR1MEN1KMT2AIDO1ALDH1A1
	SCHEMBL1680943	0.82	LTA4H (0.38)	L3MBTL1ALDH1A1SMN1; SMN2
	SCHEMBL1680959	0.74	KMT2A (0.37)	TAAR1L3MBTL1MEN1KMT2AP2RX7
	SCHEMBL7825397	0.72	TAAR1 (0.42)	TAAR1MEN1KMT2AIDO1AGXT
	SCHEMBL1680878	0.72	TAAR1 (0.50)	TAAR1MEN1KMT2AIDO1AGXT
	SCHEMBL1680459	0.71	ATM (0.41)	TAAR1ATML3MBTL1P2RX7IDO1
	SCHEMBL1680447	0.69	MAOA (0.41)	TAAR1MEN1KMT2AIDO1AGXT
	SCHEMBL29910993	0.68	ATM (0.46)	TAAR1ATML3MBTL1MEN1KMT2A
	SCHEMBL3300303	0.68	TAAR1 (0.60)	TAAR1IDO1AGXTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.