SCHEMBL1680959

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680943	0.78	LTA4H (0.38)	ALDH1A1L3MBTL1TP53SMN1; SMN2
	SCHEMBL1680485	0.75	ALOX5 (0.36)	KMT2AMEN1EPHX2TAAR1PKM
	SCHEMBL1680499	0.74	TAAR1 (0.40)	KMT2AMEN1TAAR1ALDH1A1L3MBTL1
	SCHEMBL1680564	0.70	TAAR1 (0.48)	KMT2AMEN1EPHX2TAAR1TP53
	SCHEMBL1680749	0.70	TAAR1 (0.39)	KMT2AMEN1EPHX2TAAR1PKM
	SCHEMBL15783791	0.70	MEN1 (0.38)	KMT2AMEN1ALDH1A1
	SCHEMBL1680744	0.68	NPC1 (0.42)	KMT2AMEN1TAAR1ABL1IDO1
	SCHEMBL1680660	0.67	ALDH1A1 (0.39)	KMT2AMEN1EPHX2TAAR1PKM
	SCHEMBL1968823	0.66	PKM (0.46)	KMT2ATAAR1CYP2A13PKMALDH1A1
	SCHEMBL3301625	0.65	TAAR1 (0.59)	TAAR1CYP2A13ALDH1A1L3MBTL1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.