SCHEMBL1680459

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680796	0.84	PNMT (0.39)	ATMTAAR1IDO1AGXTDAO
	SCHEMBL510447	0.82	LMNA (0.33)	TAAR1ALDH1A1MAPTIDO1SMN1; SMN2
	SCHEMBL1106846	0.82	CALM1 (0.37)	SMN1; SMN2
	SCHEMBL1680634	0.72	TAAR1 (0.50)	TAAR1IDO1AGXTDAO
	SCHEMBL4498539	0.72	TAAR1 (0.50)	TAAR1MAPTIDO1AGXTDAO
	SCHEMBL1680499	0.71	TAAR1 (0.40)	ATML3MBTL1TAAR1ALDH1A1IDO1
	SCHEMBL1680877	0.69	ALDH1A1 (0.46)	TAAR1ALDH1A1IDO1AGXTSMN1; SMN2
	SCHEMBL29910993	0.68	ATM (0.46)	ATML3MBTL1TAAR1ALDH1A1IDO1
	SCHEMBL3300303	0.68	TAAR1 (0.60)	TAAR1ALDH1A1IDO1AGXTSMN1; SMN2
	SCHEMBL4674508	0.68	ALDH1A1 (0.46)	ALDH1A1MAPTSMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.