SCHEMBL2887982

SCHEMBL2887982

CCCC1(CCC)C(=O)NC(=O)NC1=O

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.64
MMP9 P14780 8/20 0.46
MMP2 P08253 6/20 0.46
MMP8 P22894 4/20 0.46
MMP13 P45452 4/20 0.46
ALDH1A1 P00352 3/20 0.46
TP53 P04637 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
KDM4E B2RXH2 1/20 0.42
CYP3A4 P08684 1/20 0.42
GABRB3 P28472 1/20 0.42
OPRD1 P41143 1/20 0.42
GABRA2 P47869 1/20 0.42
GABRB2 P47870 1/20 0.42
MMP3 P08254 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4889487 0.90 LMNA (0.73) LMNAMMP9MMP2MMP8MMP13
SCHEMBL11721680 0.89 ALDH1A1 (0.48) LMNAMMP9MMP2MMP8MMP13
SCHEMBL11269799 0.85 LMNA (0.48) LMNAMMP9MMP2MMP8MMP13
SCHEMBL1683293 0.85 LMNA (0.58) LMNAMMP9MMP2MMP8MMP13
SCHEMBL5450754 0.81 MMP9 (0.67) LMNAMMP9MMP2MMP8MMP13
SCHEMBL468545 0.81 MMP9 (0.67) LMNAMMP9MMP2MMP8MMP13
Barbital SCHEMBL7348703 0.79 LMNA (0.90) LMNAMMP9MMP2MMP8MMP13
Barbital SCHEMBL43818 0.78 LMNA (1.00) LMNAMMP9MMP2MMP8MMP13
Barbital SCHEMBL3859278 0.78 LMNA (1.00) LMNAMMP9MMP2MMP8MMP13
Barbital SCHEMBL8746543 0.77 LMNA (0.85) LMNAMMP9MMP2MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12318729-B2 Enzymatic phase transfer solvent for CO2/H2S capture INDIAN OIL CORPORATION LIMITED (IN) 2025-06-03 US claimed
US-20250134787-A1 AMINE REAGENTS AND PROCESSES FOR ARTIFICIAL MELANIN NANOPARTICLES FOR HAIR DYES NORTHWESTERN UNIVERSITY (US) 2025-05-01 US claimed
EP-4427835-A1 CARBON CAPTURE SOLVENTS AND METHODS FOR USING SUCH SOLVENTS Carbon Clean Solutions Limited (GB) 2024-09-11 EP claimed
EP-4353403-A1 HIGH TEMPERATURE WELDING WIRE LUBRICANT FOR PREHEATED WELDING WIRE SYSTEM AND RELATED METHODS Hobart Brothers LLC (US) 2024-04-17 EP claimed
EP-3844107-B1 SODIUM BICARBONATE PRODUCTION TATA CHEMICALS EUROPE LTD (GB) 2024-04-10 EP claimed
WO-2023150205-A1 AMINE REAGENTS AND PROCESSES FOR ARTIFICIAL MELANIN NANOPARTICLES FOR HAIR DYES NORTHWESTERN UNIVERSITY (US) 2023-08-10 WO claimed
US-20230250536-A1 MODIFICATION OF METALLIC SURFACES WITH PHOSPHONIC ACIDS BIOLOGICAL DYNAMICS, INC. 2023-08-10 US claimed
EP-4179133-A1 MODIFICATION OF METALLIC SURFACES WITH PHOSPHONIC ACIDS Biological Dynamics, Inc. (US) 2023-05-17 EP claimed
WO-2023003776-A1 IN-SITU GENERATION OF NUCLEATING AGENTS FOR INDICATING DEVICES JP LABORATORIES, INC. (US) 2023-01-26 WO claimed
US-20220387400-A1 FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE Belite Bio (HK) Limited (HK) 2022-12-08 US claimed
US-20220288531-A1 NOVEL ENZYMATIC PHASE TRANSFER SOLVENT FOR CO2/H2S CAPTURE INDIAN OIL CORPORATION LIMITED (IN) 2022-09-15 US claimed
EP-4056255-A1 A NOVEL ENZYMATIC PHASE TRANSFER SOLVENT FOR CO2/H2S CAPTURE Indian Oil Corporation Limited (IN) 2022-09-14 EP claimed
US-11434142-B2 Sodium bicarbonate production Tata Chemicals Europe Limited (GB) 2022-09-06 US claimed
EP-3996714-A1 FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE Belite Bio, LLC (US) 2022-05-18 EP claimed
US-20260146545-A1 LIQUID FLUID SYSTEMS FOR TURBINE ENGINES GENERAL ELECTRIC COMPANY (US) 2026-05-28 US disclosed
US-20260144732-A1 MELANIN HAIR DYE WITH THICKENERS NORTHWESTERN UNIVERSITY (US) 2026-05-28 US disclosed
US-12637532-B2 Sulfonated polymers and compositions thereof Kraton Corporation (US) 2026-05-26 US disclosed
US-4382983-A PARTIALLY HYDROLYZED SILOXANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-05-10 US disclosed
US-4307252-A 2-Propyl-pent-4-en-1-al RUHRCHEMIE AKTIENGESELLSCHAFT (DE) 1981-12-22 US disclosed
US-4270008-A 2-Propyl-pent-4-en-1-al RUHRCHEMIE AKTIENGESELLSCHAFT (DE) 1981-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250134787-A1 AMINE REAGENTS AND PROCESSES FOR ARTIFICIAL MELANIN NANOPARTICLES FOR HAIR DYES TYR, MC1R, AADAT LMNA 2224/4885MMP9 2936/4885MMP2 2872/4885
US-20260146545-A1 LIQUID FLUID SYSTEMS FOR TURBINE ENGINES DSP, PLK4, AQP1 LMNA 632/4885MMP9 366/4885MMP2 1238/4885
US-12637532-B2 Sulfonated polymers and compositions thereof PCNA, SDC1, MSH2 LMNA 1170/4885MMP9 1616/4885MMP2 2339/4885
US-20220387400-A1 FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE RBP4, RBP1, RBM3 LMNA 962/4885MMP9 4480/4885MMP2 3546/4885
US-20260144732-A1 MELANIN HAIR DYE WITH THICKENERS TYR, MC1R, TPH1 LMNA 3092/4885MMP9 504/4885MMP2 1299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.