Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5966339 | 0.75 | ESR1 (0.42) | MAPTKMT2AHIF1AALDH1A1ALOX15 | |
| SCHEMBL9392778 | 0.75 | KMT2A (0.36) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL27780328 | 0.74 | ALDH1A1 (0.38) | HDAC6ALDH1A1ELANETSHR | |
| SCHEMBL2154648 | 0.69 | — | — | |
| SCHEMBL12394342 | 0.69 | TSHR (0.39) | ALDH1A1TSHRACHECYP3A4HSD17B10 | |
| SCHEMBL8154595 | 0.69 | ALDH1A1 (0.35) | MAPK1MAPTKMT2AALDH1A1ALOX15 | |
| SCHEMBL4924726 | 0.69 | GAA (0.34) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL23331409 | 0.68 | MAPK1 (0.33) | MAPK1ALDH1A1TAAR1ALOX15SLC6A2 | |
| SCHEMBL13583073 | 0.67 | ALDH1A1 (0.35) | MAPTALDH1A1ALOX15TSHRLMNA | |
| SCHEMBL1667 | 0.67 | ALDH1A1 (0.35) | MAPTALDH1A1ALOX15TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181250-A | Alkenyl phosphine compound and preparation method thereof | 中国石油化工股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| EP-2639233-B1 | Phosphine oxide, a process for the manufacture thereof and application thereof | CENTRUM BADAN MOLEKULARNYCH I MAKROMOLEKULARNYCH PAN (PL) | 2017-01-04 | — | — | EP | claimed |
| EP-2639233-A1 | Phosphine oxide, a process for the manufacture thereof and application thereof | Centrum Badan Molekularnych I Makromolekularnych Pan (PL) | 2013-09-18 | — | — | EP | claimed |
| CN-119176840-A | Phosphorus-containing (meth) acryl composition, method for producing same, flame-retardant resin composition, prepreg, and use thereof | 日铁化学材料株式会社 | 2024-12-24 | — | — | CN | disclosed |
| CN-118440115-A | Asymmetric synthesis method of axial chiral biaryl-aryl phosphine oxide | 上海交通大学 | 2024-08-06 | — | — | CN | disclosed |
| US-12012426-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2024-06-18 | — | — | US | disclosed |
| CN-112654630-B | Tetradentate diaminodiphosphine ligands, transition metal complexes, methods for their production and use thereof | 高砂香料工业株式会社 | 2024-05-24 | — | — | CN | disclosed |
| WO-2023167148-A1 | PHOSPHORUS-CONTAINING (METH)ACRYLOYL COMPOUND, PRODUCTION METHOD THEREFOR, FLAME-RETARDANT RESIN COMPOSITION CONTAINING PHOSPHORUS-CONTAINING (METH)ACRYLOYL COMPOUND, CURED PRODUCT, AND LAMINATED BOARD FOR ELECTRONIC CIRCUIT BOARD | 日鉄ケミカル＆マテリアル株式会社 | 2023-09-07 | — | — | WO | disclosed |
| WO-2023167019-A1 | PHOSPHORUS-CONTAINING (METH)ACRYLOYL COMPOUND, METHOD FOR PRODUCING SAME, AND FLAME-RETARDANT COMPOSITION AND LAMINATED BOARD FOR ELECTRONIC CIRCUIT BOARD CONTAINING SAME | 日鉄ケミカル＆マテリアル株式会社 | 2023-09-07 | — | — | WO | disclosed |
| CN-116655686-A | Synthesis method and application of pentavalent and trivalent tridentate phosphine ligand | 广东欧凯新材料有限公司 | 2023-08-29 | — | — | CN | disclosed |
| US-20230219983-A1 | TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2023-07-13 | — | — | US | disclosed |
| US-20110098485-A1 | BIDENTATE SECONDARY PHOSPHINE OXIDE CHIRAL LIGANDS FOR USE IN ASYMMETRIC ADDITION REACTIONS | SOLVIAS AG (CH) | 2011-04-28 | — | — | US | disclosed |
| US-20100317866-A1 | IMIDAZOLE GROUP-CONTAINING PHOSPHORUS COMPOUNDS | BASF SE (DE) | 2010-12-16 | — | — | US | disclosed |
| US-20100317866-A1 | IMIDAZOLE GROUP-CONTAINING PHOSPHORUS COMPOUNDS | BASF SE (DE) | 2010-12-16 | — | — | US | disclosed |
| CN-101868468-A | Bidentate secondary phosphine oxide chiral ligands for asymmetric addition reactions | SOLVIAS AG | 2010-10-20 | — | — | CN | disclosed |
| EP-2212340-A1 | BIDENTATE SECONDARY PHOSPHINE OXIDE CHIRAL LIGANDS FOR USE IN ASYMMETRIC ADDITION REACTIONS | Solvias AG (CH) | 2010-08-04 | — | — | EP | disclosed |
| US-20100174079-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PHOSPHOROUS COMPOUND | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE TECHNOLOGY (JP) | 2010-07-08 | — | — | US | disclosed |
| US-20090171114-A1 | Chiral Ligands Used in Transition Metal Catysts for Asymmetric Addition Reactions Especially Hydrogenation | SOLVIAS AG (CH) | 2009-07-02 | — | — | US | disclosed |
| WO-2009065783-A1 | BIDENTATE SECONDARY PHOSPHINE OXIDE CHIRAL LIGANDS FOR USE IN ASYMMETRIC ADDITION REACTIONS | SOLVIAS AG (CH) | 2009-05-28 | — | — | WO | disclosed |
| WO-2007135179-A1 | CHIRAL LIGANDS USED IN TRANSITION METAL CATALYSTS FOR ASYMMETRIC ADDITION REACTIONS ESPECIALLY HYDROGENATION | SOLVIAS AG (CH) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098485-A1 | BIDENTATE SECONDARY PHOSPHINE OXIDE CHIRAL LIGANDS FOR USE IN ASYMMETRIC ADDITION REACTIONS | H1-2, PHOSPHO1, H1-0 | MAPK1 1062/4885MAPT 4850/4885KMT2A 1813/4885 |
| US-20230219983-A1 | TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME | ADH4, ADH5, PF4 | MAPK1 4189/4885MAPT 1502/4885KMT2A 1576/4885 |
| US-12012426-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | ADH4, ADH5, PF4 | MAPK1 4189/4885MAPT 1502/4885KMT2A 1576/4885 |
| US-20090171114-A1 | Chiral Ligands Used in Transition Metal Catysts for Asymmetric Addition Reactions Especially Hydrogenation | HRH3, HRH4, HRH1 | MAPK1 1443/4885MAPT 4624/4885KMT2A 2273/4885 |
| US-20100174079-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PHOSPHOROUS COMPOUND | AGL, RPS4X, MRPL9 | MAPK1 1048/4885MAPT 3911/4885KMT2A 3742/4885 |
| US-20100317866-A1 | IMIDAZOLE GROUP-CONTAINING PHOSPHORUS COMPOUNDS | ITPA, PPIP5K2, IPMK | MAPK1 2262/4885MAPT 1288/4885KMT2A 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.