SCHEMBL1687563

SCHEMBL1687563

Cc1cccc(N(c2ccccc2)c2cc3c(c4ccccc24)-c2cc4c(cc2C3(C)C)-c2c(cc(N(c3ccccc3)c3cccc(C)c3)c3ccccc23)C4(C)C)c1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
SIGMAR1 Q99720 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL355990 0.97 SIGMAR1 (0.32) MAPTSIGMAR1
SCHEMBL802818 0.94 PDK2 (0.30) MAPTKDM4EMEN1LMNAHTT
SCHEMBL18622614 0.91
SCHEMBL10213351 0.91 PDK2 (0.32) LMNA
SCHEMBL355200 0.91
SCHEMBL2606538 0.90
SCHEMBL21253655 0.89 MAPT (0.32) MAPTSIGMAR1
SCHEMBL15895286 0.89 KDM4E (0.31) MAPTKDM4E
SCHEMBL24236169 0.89 SIGMAR1 (0.33) SIGMAR1MEN1KMT2A
SCHEMBL15895380 0.89 PDK2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3559078-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-10-25 EP disclosed
US-11737352-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-11737352-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 US disclosed
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 US disclosed
US-20230108986-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-04-06 US disclosed
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-07-12 US disclosed
US-20220199908-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2022-06-23 US disclosed
US-20210367155-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-11-25 US disclosed
EP-3571264-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-11-24 EP disclosed
US-20120319052-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-12-20 US disclosed
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-22 US disclosed
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-22 US disclosed
US-20120217449-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-08-30 US disclosed
US-20120217449-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-08-30 US disclosed
US-20120187349-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-07-26 US disclosed
US-20120187349-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-07-26 US disclosed
WO-2012045384-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-04-12 WO disclosed
US-20090184313-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2009-07-23 US disclosed
US-20090184313-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2009-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090184313-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2A1, SLCO1A2 MAPT 183/4885SIGMAR1 1760/4885KDM4E 2218/4885
US-20210367155-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES EPB41, EPB41L2, MCM4 MAPT 1516/4885SIGMAR1 1821/4885KDM4E 852/4885
US-20120187349-A1 MATERIALS FOR ELECTRONIC DEVICES SLC26A3, SLCO4C1, SLCO2A1 MAPT 1057/4885SIGMAR1 3396/4885KDM4E 3203/4885
US-20120217449-A1 MATERIALS FOR ELECTRONIC DEVICES EFNA1, DDT, ERCC1 MAPT 1295/4885SIGMAR1 3160/4885KDM4E 3591/4885
US-11737352-B2 Materials for organic electroluminescent devices EPB41, EPB41L2, MCM4 MAPT 1516/4885SIGMAR1 1821/4885KDM4E 852/4885
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES SLCO4C1, SLCO1A2, SLCO2A1 MAPT 801/4885SIGMAR1 2795/4885KDM4E 3073/4885
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices PKD1, PIEZO1, AQP1 MAPT 2733/4885SIGMAR1 2094/4885KDM4E 4609/4885
US-20120319052-A1 COMPOUNDS FOR ELECTRONIC DEVICES CYP1B1, CYP1A1, CYP2E1 MAPT 2304/4885SIGMAR1 3712/4885KDM4E 2681/4885
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES SELE, EPHA6, EPX MAPT 3046/4885SIGMAR1 3354/4885KDM4E 2986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.