SCHEMBL802818

SCHEMBL802818

Cc1cccc(N(c2ccccc2)c2cc3c(c4ccccc24)-c2cc4c(cc2C3(C)C)-c2ccccc2C4(C)C)c1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10213351 0.98 PDK2 (0.32) PDK2LMNA
SCHEMBL1687563 0.94 MAPT (0.32) KDM4EMEN1LMNAMAPTHTT
SCHEMBL1687562 0.92 MLNR (0.31) PDK2
SCHEMBL20419962 0.92 MLNR (0.31) PDK2
SCHEMBL355990 0.92 SIGMAR1 (0.32) MAPT
SCHEMBL19565234 0.91 PGR (0.32) PDK2
SCHEMBL2606538 0.90
SCHEMBL11914332 0.89 KDM4E (0.33) PDK2KDM4EMAPT
SCHEMBL21911341 0.89 PDK2 (0.31) PDK2
SCHEMBL18622614 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3457450-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-12 EP disclosed
EP-3559078-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-10-25 EP disclosed
US-11737352-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-11737352-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 US disclosed
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 US disclosed
US-20230108986-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-04-06 US disclosed
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-07-12 US disclosed
US-20220199908-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2022-06-23 US disclosed
US-20210367155-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-11-25 US disclosed
US-20110112275-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2011-05-12 US disclosed
US-20110112275-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2011-05-12 US disclosed
WO-2011054442-A2 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-05-12 WO disclosed
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2011-04-28 US disclosed
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2011-04-28 US disclosed
WO-2011035836-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-03-31 WO disclosed
WO-2011000455-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2011-01-06 WO disclosed
WO-2010136109-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-12-02 WO disclosed
WO-2010072300-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2010-07-01 WO disclosed
WO-2010049050-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2010-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210367155-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES EPB41, EPB41L2, MCM4 PDK2 1181/4885KDM4E 852/4885MEN1 493/4885
US-11737352-B2 Materials for organic electroluminescent devices EPB41, EPB41L2, MCM4 PDK2 1181/4885KDM4E 852/4885MEN1 493/4885
US-20110112275-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES LAGE3, EML4, MCM4 PDK2 2192/4885KDM4E 1167/4885MEN1 1357/4885
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices PKD1, PIEZO1, AQP1 PDK2 233/4885KDM4E 4609/4885MEN1 500/4885
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES KCNJ2, IKZF2, TERT PDK2 596/4885KDM4E 2566/4885MEN1 4210/4885
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES SELE, EPHA6, EPX PDK2 1021/4885KDM4E 2986/4885MEN1 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.