SCHEMBL16889165

SCHEMBL16889165

Cc1ccccc1-c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2ccccc2C)cc1O3

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
HTR7 P34969 3/20 0.37
MCL1 Q07820 1/20 0.36
CTSD P07339 2/20 0.35
BACE1 P56817 2/20 0.35
TRPA1 O75762 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2D6 P10635 2/20 0.35
TSHR P16473 2/20 0.35
CYP2C19 P33261 2/20 0.35
CLK4 Q9HAZ1 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP2C9 P11712 1/20 0.35
MAPK1 P28482 1/20 0.35
GRIA1 P42261 1/20 0.34
CACNG8 Q8WXS5 1/20 0.34
HTR1A P08908 1/20 0.34
LCK P06239 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29522930 1.00 CA12 (0.41) CA12CA9HTR7MCL1CTSD
SCHEMBL16890517 0.97 CA12 (0.39) CA12CA9HTR7MCL1CTSD
SCHEMBL16890804 0.95 CA12 (0.40) CA12CA9HTR7MCL1CTSD
SCHEMBL16890801 0.95 CA12 (0.38) CA12CA9HTR7MCL1CTSD
SCHEMBL16890513 0.92 CA12 (0.39) CA12CA9HTR7MCL1CTSD
SCHEMBL16891227 0.91 CA12 (0.36) CA12CA9HTR7MCL1CTSD
SCHEMBL16890797 0.90 CA12 (0.38) CA12CA9HTR7MCL1CTSD
SCHEMBL16890802 0.90 CA12 (0.38) CA12CA9HTR7MCL1CTSD
SCHEMBL23432328 0.89 CA12 (0.34) CA12CA9HTR7MCL1CYP1A2
SCHEMBL16891226 0.89 ENPP3 (0.36) CA12CA9HTR7MCL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-10-31 US disclosed
EP-3960744-B1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUND (JP) 2024-08-21 EP disclosed
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-20230096132-A1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-30 US disclosed
EP-3626722-A1 POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2020-03-25 EP disclosed
EP-3626722-A1 POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2020-03-25 EP disclosed
WO-2020045681-A1 ORGANIC ELECTROLUMINESCENT ELEMENT USING LIGHT EMITTING MATERIAL COMPOSED OF POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2020-03-05 WO disclosed
US-20200035922-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-01-30 US disclosed
US-10374166-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2019-08-06 US disclosed
US-20190027694-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2019-01-24 US disclosed
EP-3345911-A1 POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL Kwansei Gakuin Educational Foundation (JP) 2018-07-11 EP disclosed
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2015-08-20 US disclosed
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2015-08-20 US disclosed
WO-2015102118-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2015-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC CA12 2333/4885CA9 1102/4885HTR7 4205/4885
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 CA12 1612/4885CA9 2850/4885HTR7 2330/4885
US-20230096132-A1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND LAGE3, ELOC, ELOB CA12 1132/4885CA9 880/4885HTR7 4764/4885
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR CA12 4589/4885CA9 2592/4885HTR7 745/4885
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 CA12 696/4885CA9 512/4885HTR7 4266/4885
US-12029120-B2 Organic electroluminescence element and electronic device RPS10, H1-10, OR10J3 CA12 625/4885CA9 2071/4885HTR7 4745/4885
US-10374166-B2 Polycyclic aromatic compound PAH, ALK, AOC2 CA12 696/4885CA9 512/4885HTR7 4266/4885
US-20190027694-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, PAH, EBPL CA12 1232/4885CA9 837/4885HTR7 4175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.