SCHEMBL16889229

SCHEMBL16889229

c1ccc2c(c1)Oc1cc(N3c4ccccc4Oc4ccccc43)cc3c1B2c1ccccc1O3

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 7/20 0.34
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22099827 0.94 P2RX4 (0.31) P2RX4
SCHEMBL26940529 0.91 HPGD (0.32) P2RX4
SCHEMBL23633177 0.90
SCHEMBL21991426 0.89
SCHEMBL22600940 0.89 P2RX4 (0.35) P2RX4
SCHEMBL21793789 0.88 P2RX4 (0.31) P2RX4
SCHEMBL21793645 0.88 MAOA (0.41) P2RX4SMN1; SMN2
SCHEMBL17879295 0.87 KMT2A (0.31) MAPTSMN1; SMN2
SCHEMBL24000429 0.87
SCHEMBL23980958 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2023-12-14 US disclosed
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2023-12-14 US disclosed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-20230058635-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-02-23 US disclosed
US-20230059210-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-02-23 US disclosed
EP-3345911-A1 POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL Kwansei Gakuin Educational Foundation (JP) 2018-07-11 EP disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed
US-20180040821-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMITTING LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-02-08 US disclosed
US-20180040821-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMITTING LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-02-08 US disclosed
EP-3109253-A1 POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2016-12-28 EP disclosed
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2015-08-20 US disclosed
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2015-08-20 US disclosed
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2015-08-20 US disclosed
WO-2015102118-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2015-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR P2RX4 512/4885MAPT 4577/4885SMN1; SMN2 3656/4885
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition ARNT, TYR, NLRP3 P2RX4 673/4885MAPT 25/4885SMN1; SMN2 4066/4885
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 P2RX4 888/4885MAPT 949/4885SMN1; SMN2 4193/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 P2RX4 888/4885MAPT 949/4885SMN1; SMN2 4193/4885
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR P2RX4 262/4885MAPT 240/4885SMN1; SMN2 3853/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 P2RX4 888/4885MAPT 949/4885SMN1; SMN2 4193/4885
US-20180040821-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMITTING LAYER-FORMING COMPOSITION C9, TYR, CCNA1 P2RX4 3031/4885MAPT 136/4885SMN1; SMN2 4684/4885
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS ELP1, ELOVL1, L3MBTL1 P2RX4 2367/4885MAPT 1186/4885SMN1; SMN2 140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.