Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | CDK1 | P06493 | 1/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 1/20 | 0.62 |
| ▸ | CDK7 | P50613 | 1/20 | 0.62 |
| ▸ | CCNH | P51946 | 1/20 | 0.62 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.62 |
| ▸ | TCF4 | P15884 | 1/20 | 0.59 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | PTPRC | P08575 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14877794 | 0.88 | CA12 (0.76) | CA12CA1CA2CA9FFAR4 | |
| SCHEMBL3701951 | 0.85 | CA12 (0.71) | CA12CA1CA2CA9FFAR4 | |
| SCHEMBL2690296 | 0.85 | KEAP1 (0.66) | MEN1GAAKMT2ACYP19A1ALDH1A1 | |
| SCHEMBL9001319 | 0.82 | CA1 (0.67) | CA12CA1CA2CA9FFAR4 | |
| SCHEMBL14937571 | 0.81 | PGR (0.72) | CA12CA1CA2CA9FFAR4 | |
| SCHEMBL9763115 | 0.81 | HTR6 (0.79) | CA12CA1CA2CA9FFAR4 | |
| SCHEMBL30737507 | 0.81 | HTR6 (0.79) | CA12CA1CA2CA9FFAR4 | |
| SCHEMBL3259544 | 0.81 | HSD17B2 (0.72) | CA12CA1CA2CA9FFAR4 | |
| SCHEMBL28560165 | 0.81 | CA12 (0.65) | CA12CA1CA2CA9FFAR4 | |
| SCHEMBL6607079 | 0.81 | ALDH1A1 (0.71) | CA12CA1CA2CA9FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |
| EP-2311455-B1 | Compounds for nonsense suppression, and methods for their use | PTC THERAPEUTICS INC (US) | 2015-07-15 | — | — | EP | disclosed |