Sugi Predict

Sugi Predict / Compounds / SCHEMBL2184899

SCHEMBL2184899

SCHEMBL2184899

CCOC(=O)C1(COCCOC)CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ MEN1 O00255 6/20 0.37
▸ KMT2A Q03164 6/20 0.37
▸ MAPT P10636 1/20 0.37
▸ ATM Q13315 1/20 0.37
▸ ALDH1A1 P00352 2/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ MME P08473 1/20 0.34
▸ CYP4F2 P78329 1/20 0.33
▸ CYP4A11 Q02928 1/20 0.33
▸ OPRM1 P35372 1/20 0.33
▸ OPRD1 P41143 1/20 0.33
▸ HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23135868 0.85 MAPK1 (0.39) MAPK1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL13268937 0.85 OPRM1 (0.43) MAPK1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL1691121 0.83 MAPK1 (0.40) MAPK1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL19216523 0.81 SMN1; SMN2 (0.37) MAPK1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL18556 0.80 CYP2C19 (0.46) MMECYP4F2CYP4A11
SCHEMBL19216705 0.80 SMN1; SMN2 (0.41) MAPK1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL25143741 0.78 CYP4F2 (0.50) MAPK1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL1446529 0.77 MAPK1 (0.41) MAPK1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL16900591 0.76 MAPK1 (0.41) MAPK1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL1142569 0.76 SMN1; SMN2 (0.39) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2017-10-05 — — US claimed
US-20160272733-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECHNOLOGY LTD. (CN) 2016-09-22 — — US claimed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 — — US disclosed
US-10208146-B2 Catalyst component for olefin polymerization and application thereof BEIJING LIHE TECHNOLOGY LTD. (CN) 2019-02-19 — — US disclosed
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2017-12-14 — — US disclosed
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2017-10-05 — — US disclosed
US-20160272733-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECHNOLOGY LTD. (CN) 2016-09-22 — — US disclosed
EP-2342199-B1 Sulfonyl compounds which selectively modulate the CB2 receptor BOEHRINGER INGELHEIM INT (DE) 2014-02-26 — — EP disclosed
US-8372874-B2 Compounds which selectively modulate the CB2 receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-02-12 — — US disclosed
US-8372874-B2 Compounds which selectively modulate the CB2 receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-02-12 — — US disclosed
US-8372874-B2 Compounds which selectively modulate the CB2 receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-02-12 — — US disclosed
EP-2342199-A2 COMPOUNDS WHICH SELECTIVELY MODULATE THE CB2 RECEPTOR Boehringer Ingelheim International GmbH (DE) 2011-07-13 — — EP disclosed
WO-2010036631-A2 COMPOUNDS WHICH SELECTIVELY MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-04-01 — — WO disclosed
WO-2010036631-A2 COMPOUNDS WHICH SELECTIVELY MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-04-01 — — WO disclosed
US-20100076029-A1 Compounds Which Selectively Modulate The CB2 Receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-03-25 — — US disclosed
US-20100076029-A1 Compounds Which Selectively Modulate The CB2 Receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-03-25 — — US disclosed
US-20100076029-A1 Compounds Which Selectively Modulate The CB2 Receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-03-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208146-B2 Catalyst component for olefin polymerization and application thereof TEC, ETFA, TECR MAPK1 1257/4885L3MBTL1 4395/4885KDM4E 3191/4885
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B MAPK1 1884/4885L3MBTL1 3793/4885KDM4E 4599/4885
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF TEC, ETFA, TECR MAPK1 1257/4885L3MBTL1 4395/4885KDM4E 3191/4885
US-20100076029-A1 Compounds Which Selectively Modulate The CB2 Receptor CNR2, CNR1, OPRL1 MAPK1 1028/4885L3MBTL1 4671/4885KDM4E 3300/4885
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, COG7, COG4 MAPK1 3793/4885L3MBTL1 4246/4885KDM4E 4489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.