Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.50 |
| ▸ | ITGAL | P20701 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23787378 | 0.84 | ITGB2 (0.56) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL22608018 | 0.80 | ITGB2 (0.58) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL10849873 | 0.78 | ITGB2 (0.53) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL28274103 | 0.78 | ITGB2 (0.58) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL22608013 | 0.78 | ITGB2 (0.56) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL28035475 | 0.77 | CYP3A4 (0.56) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL163397 | 0.77 | ITGB2 (0.60) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL17846596 | 0.77 | CYP3A4 (0.64) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL151336 | 0.77 | ITGB2 (0.60) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL27043238 | 0.77 | ITGB2 (0.60) | CYP3A4SLC7A5ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180353607-A1 | LIPIDS FOR DELIVERY OF THERAPEUTICS | MARINA BIOTECH INC (US) | 2018-12-13 | — | — | US | claimed |
| US-9821067-B2 | Lipopeptides for delivery of nucleic acids | MARINA BIOTECH, INC. (US) | 2017-11-21 | — | — | US | claimed |
| US-20160058870-A1 | LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS | MARINA BIOTECH INC (US) | 2016-03-03 | — | — | US | claimed |
| US-9220785-B2 | Lipopeptides for delivery of nucleic acids | MARINA BIOTECH, INC. (US) | 2015-12-29 | — | — | US | claimed |
| US-20130231382-A1 | LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS | MARINA BIOTECH, INC. (US) | 2013-09-05 | — | — | US | claimed |
| US-20100240731-A1 | LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS | MDRNA, INC. (US) | 2010-09-23 | — | — | US | claimed |
| CN-101674853-A | Amino acid lipids and uses thereof | NASTECH PHARM CO | 2010-03-17 | — | — | CN | claimed |
| US-20080317839-A1 | AMINO ACID LIPIDS AND USES THEREOF | NASTECH PHARMACEUTICAL COMPANY INC. (US) | 2008-12-25 | — | — | US | claimed |
| EP-3434259-A1 | AMINO ACID LIPIDS AND USES THEREOF | Marina Biotech, Inc. (US) | 2019-01-30 | — | — | EP | disclosed |
| US-20180353607-A1 | LIPIDS FOR DELIVERY OF THERAPEUTICS | MARINA BIOTECH INC (US) | 2018-12-13 | — | — | US | disclosed |
| US-9821067-B2 | Lipopeptides for delivery of nucleic acids | MARINA BIOTECH, INC. (US) | 2017-11-21 | — | — | US | disclosed |
| US-9731016-B2 | Tyrosine-based lipids for delivery of therapeutics | MARINA BIOTECH, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20160206739-A1 | TYROSINE-BASED LIPIDS FOR DELIVERY OF THERAPEUTICS | MARINA BIOTECH INC (US) | 2016-07-21 | — | — | US | disclosed |
| US-9339461-B2 | Arginine-based lipids for delivery of therapeutics | MARINA BIOTECH, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20110130327-A1 | Multi-Arm Amines and Uses Thereof | MARINA BIOTECH, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| US-7939505-B2 | Amino acid lipids and uses thereof | MARINA BIOTECH, INC. (US) | 2011-05-10 | — | — | US | disclosed |
| US-20100112042-A1 | Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics | MDRNA, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2010045512-A2 | PROCESSES AND COMPOSITIONS FOR LIPOSOMAL AND EFFICIENT DELIVERY OF GENE SILENCING THERAPEUTICS | MDRNA , INC. (US) | 2010-04-22 | — | — | WO | disclosed |
| CN-101674853-A | Amino acid lipids and uses thereof | NASTECH PHARM CO | 2010-03-17 | — | — | CN | disclosed |
| US-20080317839-A1 | AMINO ACID LIPIDS AND USES THEREOF | NASTECH PHARMACEUTICAL COMPANY INC. (US) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130231382-A1 | LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS | LNPEP, LPXN, SLC27A1 | CYP3A4 4883/4885SLC7A5 109/4885ITGB2 4371/4885 |
| US-20160206739-A1 | TYROSINE-BASED LIPIDS FOR DELIVERY OF THERAPEUTICS | ABL1, LCK, ERBB2 | CYP3A4 4864/4885SLC7A5 170/4885ITGB2 3322/4885 |
| US-20080317839-A1 | AMINO ACID LIPIDS AND USES THEREOF | AADAT, AARS1, ABAT | CYP3A4 4843/4885SLC7A5 19/4885ITGB2 3699/4885 |
| US-20110130327-A1 | Multi-Arm Amines and Uses Thereof | SNRPE, SNRPA, ADAR | CYP3A4 4865/4885SLC7A5 53/4885ITGB2 2556/4885 |
| US-20160058870-A1 | LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS | LNPEP, LPXN, SLC27A1 | CYP3A4 4883/4885SLC7A5 125/4885ITGB2 4476/4885 |
| US-20100240731-A1 | LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS | LNPEP, LPXN, SLC27A1 | CYP3A4 4883/4885SLC7A5 109/4885ITGB2 4371/4885 |
| US-20100112042-A1 | Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics | SLC27A2, LYPLA2, SLC47A2 | CYP3A4 4747/4885SLC7A5 256/4885ITGB2 921/4885 |
| US-20180353607-A1 | LIPIDS FOR DELIVERY OF THERAPEUTICS | APOB, ABHD16A, LIPA | CYP3A4 4864/4885SLC7A5 86/4885ITGB2 3547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.