Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | GLA | P06280 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | IGLV6-57 | P01721 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
| ▸ | CASP7 | P55210 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16985192 | 0.92 | MAOA (0.52) | ALDH1A1GLAHPGDCYP3A4CASP1 | |
| SCHEMBL16985202 | 0.87 | AGER (0.54) | ALDH1A1HPGDHSD17B10KDM4EGAA | |
| SCHEMBL16296942 | 0.82 | ALDH1A1 (0.49) | ALDH1A1GLAL3MBTL1IGLV6-57HPGD | |
| SCHEMBL3950391 | 0.81 | ALDH1A1 (0.68) | ALDH1A1GLAL3MBTL1IGLV6-57HPGD | |
| SCHEMBL1752667 | 0.81 | ALDH1A1 (0.70) | ALDH1A1GLAL3MBTL1IGLV6-57HPGD | |
| SCHEMBL8813329 | 0.80 | IGLV6-57 (0.47) | ALDH1A1GLAL3MBTL1IGLV6-57HPGD | |
| SCHEMBL7230127 | 0.78 | ALDH1A1 (0.67) | ALDH1A1GLAL3MBTL1IGLV6-57HPGD | |
| SCHEMBL29582092 | 0.78 | ALDH1A1 (0.67) | ALDH1A1GLAL3MBTL1IGLV6-57HPGD | |
| SCHEMBL25411899 | 0.78 | ALOX15 (0.46) | ALDH1A1GLAL3MBTL1IGLV6-57HPGD | |
| SCHEMBL9279833 | 0.77 | ALDH1A1 (0.49) | ALDH1A1GLAL3MBTL1IGLV6-57HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253185-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2019-04-09 | — | — | US | disclosed |
| US-20170145214-A1 | FLUOROGENIC PH-SENSITIVE DYES AND THEIR METHODS OF USE (II) | Life Technologies Corporation | 2017-05-25 | — | — | US | disclosed |
| US-20170145214-A1 | FLUOROGENIC PH-SENSITIVE DYES AND THEIR METHODS OF USE (II) | Life Technologies Corporation | 2017-05-25 | — | — | US | disclosed |
| US-9599622-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2017-03-21 | — | — | US | disclosed |
| US-9599622-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | Life Technologies Corporation | 2015-08-27 | — | — | US | disclosed |
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | Life Technologies Corporation | 2015-08-27 | — | — | US | disclosed |
| US-20150218379-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
| US-20150218379-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253185-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | ALPG, XDH, ASAH2 | ALDH1A1 861/4885GLA 74/4885L3MBTL1 4091/4885 |
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | ALPG, XDH, HEXD | ALDH1A1 960/4885GLA 52/4885L3MBTL1 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.